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Ophthalmia neonatorum treatment and prophylaxis: IPOSC global study

Ofira Zloto1,2, Almutez Gharaibeh3, Eedy Mezer4

  • 1Department of Ophthalmology, Sheba Medical Center, Goldschleger Eye Institute, Tel Hashomer, 52621, Israel.

Graefe'S Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie
|January 27, 2016
PubMed

Insights

Ophthalmia neonatorum (ON) incidence is low, with Chlamydia trachomatis as the primary cause. Most infants receive erythromycin for treatment and prophylaxis, according to pediatric ophthalmologists.

Area of Science:

  • Ophthalmology
  • Neonatal Care
  • Infectious Diseases

Background:

  • Ophthalmia neonatorum (ON) characteristics among pediatric ophthalmologists are not well-defined.
  • Understanding current practices is crucial for managing this neonatal condition.

Purpose of the Study:

  • To investigate the incidence, diagnosis, treatment, and prophylaxis of ophthalmia neonatorum (ON).
  • To gather data from members of the American Association of Paediatric Ophthalmology and Strabismus (AAPOS).

Main Methods:

  • A web-based survey was distributed to AAPOS members via email.
  • The survey collected data on ON incidence, etiology, diagnosis, treatment, and prophylaxis globally.

Main Results:

  • 291 ophthalmologists responded; most (52.94%) were from North America.
  • The most frequent pathogen identified was Chlamydia trachomatis (35.37%).
  • Erythromycin was the predominant treatment (85.21% for early-onset, 75.09% for late-onset) and prophylactic agent (71.50% for prophylaxis).

Conclusions:

  • The incidence of ON per practitioner is typically 0-5 cases annually.
  • Chlamydia trachomatis is the leading cause of ON.
  • Prophylaxis and treatment are widely administered to affected infants.
Abstract

Keywords:
AAPOSChlamydia trachomatisConjunctivitisIPOSCNeisseria gonorrhoeaeOphthalmia neonatorumProphylaxis

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