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[SSRIs for adolescents with medically unexplained symptoms].
Suzanne C van Bronswijk1, Judith M Lionarons, Antonia Stupp
1Maastricht UMC+, Psychiatrie en Psychologie, afd. Kinder- en Jeugdpsychiatrie, Maastricht.
Medically unexplained symptoms (MUS) in adolescents can cause significant impairment. Selective serotonin reuptake inhibitors (SSRIs) show promise as an effective treatment, improving adolescent functioning.
Area of Science:
- Adolescent medicine
- Psychiatry
- Clinical psychology
Background:
- Medically unexplained symptoms (MUS) are common in adolescents, leading to healthcare overuse and functional difficulties.
- Existing treatments for adolescent MUS are often ineffective, incurring substantial societal costs.
Observation:
- Two 15-year-old girls with a history of severe MUS and affective symptoms presented with functional impairment.
- Previous treatments for these adolescents were unsuccessful.
Findings:
- Treatment with selective serotonin reuptake inhibitors (SSRIs) led to significant improvements in general functioning for both patients.
- These positive outcomes were sustained at four to five-month follow-up.
Implications:
- MUS significantly impacts adolescents, their families, and society.
- SSRIs represent a potential therapeutic option for adolescent MUS, warranting further investigation.
- Additional research is crucial to validate SSRI efficacy in adolescent populations.
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