[THE DIAGNOSTIC AND TREATMENT ALGORITHM FOR PATIENTS WITH OBSTRUCTIVE JAUNDICE SYNDROME]

Area of Science:

• Gastroenterology and Hepatology
• Surgical Oncology
• Medical Diagnostics

Background:

• Jaundice is a common complication of hepatopancreatoduodenal diseases, including tumors and benign conditions.
• Obstructive cholestasis presents significant therapeutic and diagnostic challenges.
• Current management strategies require optimization for improved patient outcomes.

Purpose of the Study:

• To compare the efficacy of standard therapeutic and diagnostic measures against a novel algorithm for managing jaundice in hepatopancreatoduodenal diseases.
• To evaluate the impact of a proposed diagnostic and treatment algorithm on patient mortality and postoperative complication rates.

Main Methods:

• Comparative analysis of therapeutic and diagnostic approaches for jaundice.
• Retrospective study involving two groups of patients with obstructive cholestasis (858 in the main group, 869 in the control group).
• Implementation of a proposed algorithm for diagnosis and treatment in the main study group.

Main Results:

• The group utilizing the proposed diagnostic and treatment algorithm demonstrated superior outcomes.
• Significantly lower mortality rates were observed in the main group compared to the control group.
• A notable reduction in the incidence of postoperative complications was achieved with the proposed algorithm.

Conclusions:

• The proposed diagnostic and treatment algorithm offers a more effective approach to managing jaundice complicating hepatopancreatoduodenal diseases.
• Implementing this algorithm can lead to improved patient survival and reduced postoperative morbidity.
• This strategy holds promise for optimizing care in patients with obstructive cholestasis.