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Updated: Mar 26, 2026

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance
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[CLINICAL PERFORMANCE OF DIFFERENT METHODS FOR CERVICAL SCREENING].

D Atanasova, V Zlatkov

    Akusherstvo I Ginekologiia
    |January 29, 2016
    PubMed
    Summary
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    Cervical cancer screening in Bulgaria shows cytology as the most effective method. Spectrophotometric analysis with TruScreen® offers a viable alternative when cytology is unavailable, being user-friendly and well-accepted by women.

    Area of Science:

    • Oncology
    • Gynecology
    • Public Health

    Background:

    • Cervical cancer presents a significant health challenge, particularly affecting women of active age.
    • Bulgaria faces a concerning increasing trend in cervical cancer morbidity and mortality.
    • Timely diagnosis is crucial for effective cervical cancer management.

    Purpose of the Study:

    • To compare the clinical performance of cervical cytology with alternative screening methods.
    • To evaluate visual inspection with acetic acid (VIA), visual inspection with Lugol's iodine (VILI), and spectrophotometric analysis (TruScreen®).
    • To identify optimal cervical cancer screening strategies for diverse healthcare settings.

    Main Methods:

    • A prospective study involving 317 women aged 18-65.

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  • Participants were categorized into four groups: cytology, VIA, VILI, and TruScreen® spectrophotometry.
  • Clinical performance of each method was assessed for cervical screening efficacy.

    • Main Results:

    • Cytology remains the gold standard for cervical cancer screening.
    • Spectrophotometric analysis using TruScreen® is a suitable alternative for primary screening when cytology services are limited.
    • Visual inspection with acetic acid (VIA) is a feasible option if TruScreen® is unavailable.

    Conclusions:

    • Cytology is the most appropriate screening method for cervical cancer.
    • TruScreen® offers a valuable, real-time, user-friendly, and well-accepted alternative for primary cervical screening.
    • VIA serves as a practical option for cervical screening in resource-limited settings.