Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Treatment Resistant Cancers02:56

Treatment Resistant Cancers

3.9K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.9K
Treatment Resistent Cancers02:56

Treatment Resistent Cancers

1.5K
1.5K
Tumor Immunotherapy01:27

Tumor Immunotherapy

2.2K
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
2.2K
Tumor Progression02:07

Tumor Progression

7.8K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
7.8K
Tumor Progression02:07

Tumor Progression

3.5K
3.5K
Cancer Therapies02:49

Cancer Therapies

10.6K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
10.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical relevance of gene expression in localized and metastatic prostate cancer exemplified by FABP5.

World journal of urology·2019
Same author

[Ectopic thymic tissue and ectopic thymic tumors].

Der Pathologe·2018
Same author

Novel insights into a reputably irreversible process: combined mRNA and miRNA profiling of tissue from vesicourethral anastomotic stenosis after radical prostatectomy.

World journal of urology·2017
Same author

[True thymic hyperplasia : Differential diagnosis of thymic mass lesions in neonates and children].

Der Pathologe·2017
Same author

[Thymomas].

Der Pathologe·2016
Same author

[Thymic carcinomas].

Der Pathologe·2016

Related Experiment Video

Updated: Mar 26, 2026

Spontaneous Murine Model of Anaplastic Thyroid Cancer
05:39

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Published on: February 3, 2023

2.4K

[Thymus cancers: A clinical observation].

H Grosch1, H Hoffmann2, C-A Weis3

  • 1Abteilung Onkologie, Thoraxklinik Heidelberg, Amalienstraße 5, 69126, Heidelberg, Deutschland. heidrun.grosch@med.uni-heidelberg.de.

Der Pathologe
|January 29, 2016
PubMed
Summary

Rare thymic tumors, including thymomas and thymic carcinomas, require tailored treatments. The new TNM staging system aids in selecting optimal therapeutic strategies for these uncommon thoracic neoplasms.

Keywords:
Carcinoma, thymicMyasthenia gravisParaneoplastic syndromesThymic carcinoid tumorThymoma

More Related Videos

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
03:55

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

1.1K
Author Spotlight: Unveiling Transmembrane Protein Family-Related Markers in Gastric Cancer and Implications for Targeted Therapies
07:47

Author Spotlight: Unveiling Transmembrane Protein Family-Related Markers in Gastric Cancer and Implications for Targeted Therapies

Published on: September 15, 2023

2.4K

Related Experiment Videos

Last Updated: Mar 26, 2026

Spontaneous Murine Model of Anaplastic Thyroid Cancer
05:39

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Published on: February 3, 2023

2.4K
Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
03:55

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

1.1K
Author Spotlight: Unveiling Transmembrane Protein Family-Related Markers in Gastric Cancer and Implications for Targeted Therapies
07:47

Author Spotlight: Unveiling Transmembrane Protein Family-Related Markers in Gastric Cancer and Implications for Targeted Therapies

Published on: September 15, 2023

2.4K

Area of Science:

  • Oncology
  • Thoracic Surgery

Background:

  • Thymic tumors (thymomas, thymic carcinomas, carcinoid tumors) are rare, with an incidence of 0.13/100,000.
  • These neoplasms exhibit diverse histologic and biologic features, ranging from indolent to aggressive behavior with metastasis.

Purpose of the Study:

  • To review current literature on the epidemiology, classification, and therapeutic approaches for thymic tumors.
  • To highlight the importance of the new TNM classification for treatment selection.

Main Methods:

  • A comprehensive literature search was conducted to identify recent findings.
  • The review focused on epidemiology, classification, and treatment modalities.

Main Results:

  • Surgical resection is primary for Stage I-II thymomas; multimodal treatment is recommended for Stage III and pleural dissemination.
  • Thymic tumors demonstrate chemosensitivity, while targeted therapies are reserved for palliative care post-chemotherapy failure.

Conclusions:

  • The updated TNM (Tumor, Node, Metastasis) classification system is crucial for optimizing treatment strategies for thymic malignancies.
  • Accurate staging is essential for guiding therapeutic decisions in patients with thymic tumors.