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Updated: Mar 26, 2026
Spontaneous Murine Model of Anaplastic Thyroid Cancer
Published on: February 3, 2023
[Thymus cancers: A clinical observation]
H Grosch1, H Hoffmann2, C-A Weis3
1Abteilung Onkologie, Thoraxklinik Heidelberg, Amalienstraße 5, 69126, Heidelberg, Deutschland. heidrun.grosch@med.uni-heidelberg.de.
Introduction:
Thymic tumors including thymomas, thymic carcinomas, and thymic carcinoid tumors are rare tumors with an incidence of 0.13/100,000.
Materials And Methods:
A literature search was performed to identify recent findings on epidemiology, classification, and various therapeutic approaches.
Results:
These tumors with a wide spectrum of histologic and biologic features may be clinically unapparent for a long time or show a very aggressive behavior with local invasion and distant metastases. Surgical resection is the mainstay in stage I and II thymomas, whereas in stage III thymomas and in thymomas with pleural dissemination surgery in context of a multimodal treatment should be discussed. Thymic tumors are chemoreactive. Targeted therapies show poor results and should only be considered in the palliative situation after failure of chemotherapy.
Conclusion:
The new TNM (T: tumor, N: node, M: metastasis) classification of thymic tumors will help to identify the best treatment options.
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