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Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy
Published on: April 9, 2019
Image fusion and navigation platforms for percutaneous image-guided interventions
Manoj Rajagopal1, Aradhana M Venkatesan2
1Department of Diagnostic and Interventional Imaging, University of Texas Medical Center at Houston, 6431 Fannin Street, 2.130B, Houston, TX, 77030, USA.
Abstract:
Image-guided interventional procedures, particularly image guided biopsy and ablation, serve an important role in the care of the oncology patient. The need for tumor genomic and proteomic profiling, early tumor response assessment and confirmation of early recurrence are common scenarios that may necessitate successful biopsies of targets, including those that are small, anatomically unfavorable or inconspicuous. As image-guided ablation is increasingly incorporated into interventional oncology practice, similar obstacles are posed for the ablation of technically challenging tumor targets. Navigation tools, including image fusion and device tracking, can enable abdominal interventionalists to more accurately target challenging biopsy and ablation targets. Image fusion technologies enable multimodality fusion and real-time co-displays of US, CT, MRI, and PET/CT data, with navigational technologies including electromagnetic tracking, robotic, cone beam CT, optical, and laser guidance of interventional devices. Image fusion and navigational platform technology is reviewed in this article, including the results of studies implementing their use for interventional procedures. Pre-clinical and clinical experiences to date suggest these technologies have the potential to reduce procedure risk, time, and radiation dose to both the patient and the operator, with a valuable role to play for complex image-guided interventions.
Insights
Image-guided biopsy and ablation use navigation tools like image fusion for challenging cancer targets. These technologies improve accuracy and reduce risks for interventional oncology procedures.
Area of Science:
- Interventional Oncology
- Medical Imaging
- Surgical Navigation
Background:
- Image-guided interventions are crucial for oncology patient care, especially for biopsies and ablations.
- Targeting small, difficult, or inconspicuous tumors presents significant challenges in interventional oncology.
- Accurate tumor profiling and response assessment necessitate precise biopsy techniques.
Purpose of the Study:
- To review image fusion and navigation technologies for image-guided interventional procedures.
- To highlight the application of these tools in overcoming challenges in biopsy and ablation targeting.
- To assess the potential benefits of these advanced navigation platforms.
Main Methods:
- Review of image fusion technologies enabling multimodality data display (US, CT, MRI, PET/CT).
- Examination of navigational technologies including electromagnetic tracking, robotic, cone beam CT, optical, and laser guidance.
- Analysis of pre-clinical and clinical studies on the use of these platforms in interventional procedures.
Main Results:
- Navigation tools, including image fusion and device tracking, enhance targeting accuracy for challenging biopsy and ablation sites.
- These technologies facilitate multimodality image fusion for real-time guidance.
- Studies indicate potential for reduced procedure risk, time, and radiation exposure for patients and operators.
Conclusions:
- Image fusion and navigation platforms offer significant potential for complex image-guided interventions in oncology.
- These technologies can improve the safety and efficiency of targeting difficult tumor sites.
- Advanced navigation plays a valuable role in advancing interventional oncology practice.
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