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Updated: Mar 26, 2026

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy
Published on: April 9, 2019
Image fusion and navigation platforms for percutaneous image-guided interventions.
Manoj Rajagopal1, Aradhana M Venkatesan2
1Department of Diagnostic and Interventional Imaging, University of Texas Medical Center at Houston, 6431 Fannin Street, 2.130B, Houston, TX, 77030, USA.
Image-guided biopsy and ablation use navigation tools like image fusion for challenging cancer targets. These technologies improve accuracy and reduce risks for interventional oncology procedures.
Area of Science:
- Interventional Oncology
- Medical Imaging
- Surgical Navigation
Background:
- Image-guided interventions are crucial for oncology patient care, especially for biopsies and ablations.
- Targeting small, difficult, or inconspicuous tumors presents significant challenges in interventional oncology.
- Accurate tumor profiling and response assessment necessitate precise biopsy techniques.
Purpose of the Study:
- To review image fusion and navigation technologies for image-guided interventional procedures.
- To highlight the application of these tools in overcoming challenges in biopsy and ablation targeting.
- To assess the potential benefits of these advanced navigation platforms.
Main Methods:
- Review of image fusion technologies enabling multimodality data display (US, CT, MRI, PET/CT).
- Examination of navigational technologies including electromagnetic tracking, robotic, cone beam CT, optical, and laser guidance.
- Analysis of pre-clinical and clinical studies on the use of these platforms in interventional procedures.
Main Results:
- Navigation tools, including image fusion and device tracking, enhance targeting accuracy for challenging biopsy and ablation sites.
- These technologies facilitate multimodality image fusion for real-time guidance.
- Studies indicate potential for reduced procedure risk, time, and radiation exposure for patients and operators.
Conclusions:
- Image fusion and navigation platforms offer significant potential for complex image-guided interventions in oncology.
- These technologies can improve the safety and efficiency of targeting difficult tumor sites.
- Advanced navigation plays a valuable role in advancing interventional oncology practice.
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