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Updated: Mar 26, 2026

Murine Fecal Isolation and Microbiota Transplantation
Published on: May 26, 2023
Gut microbiome as a novel cardiovascular therapeutic target
Vishal Singh1, Beng San Yeoh1, Matam Vijay-Kumar2
1Department of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Abstract:
Over the last two decades, our understanding of gut microbiotal composition and its association with intra-intestinal and extra-intestinal diseases including risk factors of cardiovascular disease (CVD) namely metabolic syndrome and atherosclerosis, have been increased exponentially. A pertinent question which often arises in researchers' community is on how to manipulate the gut microbial ecology to 'cure' the cardiovascular risk factors. Accordingly, in this review we summarized the potential strategies, based on our current knowledge on gut microbiota in modulating CVD, how gut microbiota can be therapeutically exploited by targeting their metabolic activity to alleviate the risk factors of CVD.
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