Related Experiment Video
Updated: Mar 26, 2026

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
Published on: October 11, 2018
A COMPARISON OF THE PREDICTIVE ACCURACY OF A POOLING AND A SUBGROUPING PREDICTION STRATEGY
Abstract:
The subgrouping strategy has been employed in a number of studies (Fredriksen & Gilbert, 1960; Fredriksen & Melville, 1964; Ghiselli, 1956; Klein, Rock & Evans, 1968; Rock, Evans & Klein, 1969; Malnig, 1969). In each of these studies it was shown that after partitioning a sample into g subgroups and performing a separate regression analysis within each group, one could identify one or more subgroups having a larger multiple correlation than the total sample regression. An important question is whether this type of result will be maintained under cross validation.
Related Concept Videos
Sampling Plans
Random sampling is a method where each member of the population has an equal chance of being selected for the sample. It involves selecting individuals randomly, often using random number generators or lottery-type methods. For example, when analyzing the properties of a...
Stratified Sampling Method
To choose a stratified sample, divide the population into groups called strata and then take a...
Comparing the Survival Analysis of Two or More Groups
Prediction Intervals
However, the point estimate is most likely not the exact value of the population parameter, but close to it. After calculating point estimates, we construct interval estimates, called confidence intervals or prediction intervals. This prediction interval comprises a range of values unlike the point estimate and is a better predictor of the observed sample value, y.
Predicting Products: Substitution vs. Elimination
The following factors can influence the mechanisms competing against each other:
Sensitivity, Specificity, and Predicted Value
Sensitivity is the...
