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Dietary Micronutrient Intake and Micronutrient Status in Patients With Chronic Stable Heart Failure: An Observational
Nicholas A McKeag1, Michelle C McKinley, Mark T Harbinson
1Nicholas A. McKeag, MB, BCh, PhD Clinical Research Fellow, Centre for Public Health, School of Medicine, Dentistry & Biomedical Sciences, Queen's University, and The Heart Centre, Belfast Health & Social Care Trust, United Kingdom. Michelle C. McKinley, PhD Senior Lecturer, Centre for Public Health, School of Medicine, Dentistry & Biomedical Sciences, Queen's University, Belfast, United Kingdom. Mark T. Harbinson, MD Senior Lecturer, Centre for Medical Education, School of Medicine, Dentistry & Biomedical Sciences, Queen's University, and The Heart Centre, Belfast Health & Social Care Trust, United Kingdom. Ann McGinty, PhD Lecturer, Centre for Public Health, School of Medicine, Dentistry & Biomedical Sciences, Queen's University, Belfast, United Kingdom. Charlotte E. Neville, PhD Research Fellow, Centre for Public Health, School of Medicine, Dentistry & Biomedical Sciences, Queen's University, Belfast, United Kingdom. Jayne V. Woodside, PhD Professor, Centre for Public Health, School of Medicine, Dentistry & Biomedical Sciences, Queen's University, Belfast, United Kingdom. Pascal P. McKeown, MD Professor, Centre for Medical Education, School of Medicine, Dentistry & Biomedical Sciences, Queen's University, and The Heart Centre, Belfast Health & Social Care Trust, United Kingdom.
Heart failure patients often have low micronutrient levels, with over 75% showing vitamin D deficiency. Many also have inadequate dietary intake of essential vitamins and minerals, impacting their health outcomes.
Area of Science:
- Cardiology
- Nutritional Science
- Clinical Medicine
Background:
- Observational studies indicate a link between reduced micronutrient status and adverse prognosis in heart failure patients.
- Reduced dietary intake of micronutrients is a potential mechanism for this deficiency in heart failure.
- Micronutrient deficiencies may contribute to the progression and severity of heart failure.
Purpose of the Study:
- To evaluate the dietary intake of micronutrients in heart failure patients.
- To assess the blood micronutrient status in individuals with heart failure.
- To identify common deficiencies, particularly vitamin D, in this population.
Main Methods:
- Dietary intake assessed using a validated food frequency questionnaire in 79 outpatients with chronic stable heart failure.
- Micronutrient blood concentrations, including vitamin D, measured from fasting blood samples.
- Analysis focused on comparing intake and status against established reference nutrient intakes.
Main Results:
- Over 20% of patients had intakes below recommended levels for multiple micronutrients, including riboflavin, vitamin D, vitamin A, calcium, magnesium, potassium, zinc, copper, selenium, and iodine.
- Vitamin D deficiency (plasma 25-hydroxy-vitamin D <50 nmol/L) was prevalent, affecting 75.6% of patients.
- Inadequate intake was also noted for several other key micronutrients, suggesting widespread nutritional concerns.
Conclusions:
- Vitamin D deficiency is highly common in patients with heart failure.
- A significant proportion of heart failure patients exhibit insufficient dietary intake of vitamin D and other essential micronutrients.
- These findings highlight the need for nutritional assessment and intervention in heart failure management.
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