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Related Concept Videos

Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

345
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
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Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

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Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

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Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

802
As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
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Nursing Process for Patient and Caregiver Teaching II: Planning and Implementation01:24

Nursing Process for Patient and Caregiver Teaching II: Planning and Implementation

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Planning for learning involves the development of a teaching plan. Teaching plans are similar to nursing care plans—both follow the steps of the nursing process. Planning in the teaching process involves setting goals and outcomes. Here, goals identify what a patient needs to achieve to understand a healthcare topic better, whereas the outcomes are the action to be performed by the patient to achieve the goal within a timeframe. For example, if the goal is to educate the patient about...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism

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Geriatric patients show significant variation in how their bodies process medications, which can change how effective and safe treatments are. The liver is the primary organ where drug metabolism occurs, involving two main types of chemical reactions: phase I and II. Phase I metabolism is driven by the cytochrome P450 enzyme system, which includes key types such as CYP3A, CYP2D6, and CYP2C9. Research indicates that while aging doesn't notably alter the levels or activity of these enzymes, it...
324

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Generation of Comprehensive Thoracic Oncology Database - Tool for Translational Research
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Geriatric Oncology Program Development and Gero-Oncology Nursing.

Mary Pat Lynch, Dana Marcone DeDonato, Ann Kutney-Lee

    Seminars in Oncology Nursing
    |February 3, 2016
    PubMed
    Summary

    Geriatric oncology care requires an interdisciplinary approach. Developing specialized programs and workforce training is crucial for meeting the complex needs of older cancer patients.

    Keywords:
    Geriatric oncologyadministrationcancerolder adultsoncology

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    Generation of Comprehensive Thoracic Oncology Database - Tool for Translational Research
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    Area of Science:

    • Geriatric Oncology
    • Cancer Care for Older Adults

    Background:

    • Older adults represent a growing population of cancer patients with unique needs.
    • Current care models may not adequately address the complexities of aging and cancer.

    Purpose of the Study:

    • Critically analyze existing approaches to geriatric oncology care.
    • Identify priority areas for developing geriatric oncology programs.
    • Recommend strategies for enhancing care for older adults with cancer.

    Main Methods:

    • Systematic review of published articles and reports.
    • Literature search conducted for publications between 1999 and 2015.

    Main Results:

    • Analysis of current care practices in geriatric oncology.
    • Identification of gaps in program development and service delivery.

    Conclusions:

    • An interdisciplinary model integrating holistic geriatric assessment is essential for patient-centered care.
    • Nursing leaders must drive workforce development and program creation in geriatric oncology.
    • Specialized programs are needed to address the comprehensive needs of older cancer patients.