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Viral hepatitis vaccination during pregnancy.
Yueyuan Zhao1, Hui Jin1,2, Xuefeng Zhang3
1a School of Public Health, Southeast University , Nanjing , China.
Human Vaccines & Immunotherapeutics
|February 3, 2016
Summary
Viral hepatitis poses a significant global health risk, particularly for pregnant women. While vaccines exist for hepatitis A, B, and E, more data is needed on their safety and efficacy during pregnancy.
Area of Science:
- Public Health
- Infectious Diseases
- Vaccinology
Background:
- Viral hepatitis is a major global health concern.
- It frequently causes jaundice and complications in pregnant women, with potential for mother-to-child transmission.
- This transmission increases disease burden and reduces quality of life.
Purpose of the Study:
- To review the current status of viral hepatitis vaccination in the context of pregnancy.
- To highlight the need for more evidence regarding the safety and efficacy of vaccines during pregnancy.
Main Methods:
- Literature review of existing studies on viral hepatitis vaccines.
- Analysis of recommendations from immunization practices committees.
- Assessment of available data on vaccine efficacy and safety in pregnant populations.
Main Results:
- Vaccines are available for hepatitis A, B, and E for the general population.
- Emergency vaccination for hepatitis A and B during pregnancy is accepted when benefits outweigh risks.
- Limited trial data exist on the efficacy and safety of hepatitis B and E vaccines in pregnant women.
Conclusions:
- Further research is essential to establish the safety and efficacy of hepatitis B and E vaccines for pregnant women.
- Evidence-based recommendations for vaccination during pregnancy require more robust data.
- Addressing viral hepatitis in pregnancy is crucial for maternal and infant health outcomes.
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