Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Menstrual Cycle01:19

The Menstrual Cycle

5.9K
The menstrual cycle is a recurrent sequence of changes in the uterine endometrium, specifically its functional layer, the stratum functionalis. This cycle prepares the uterus for potential pregnancy. This cycle typically spans 21–35 days, averaging 28 days, and aligns with the ovarian cycle, regulated by fluctuating levels of ovarian hormones, primarily estrogen and progesterone.
The menstrual phase occurs from days 1 to 5 and involves the shedding of the stratum functionalis, as a...
5.9K
Hormonal Regulation of the Menstrual Cycle01:22

Hormonal Regulation of the Menstrual Cycle

2.2K
The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
2.2K
Model Approaches for Pharmacokinetic Data: Distributed Parameter Models01:06

Model Approaches for Pharmacokinetic Data: Distributed Parameter Models

310
Pharmacokinetic models are mathematical constructs that represent and predict the time course of drug concentrations in the body, providing meaningful pharmacokinetic parameters. These models are categorized into compartment, physiological, and distributed parameter models.
The distributed parameter models are specifically designed to account for variations and differences in some drug classes. This model is particularly useful for assessing regional concentrations of anticancer or...
310
Model Approaches for Pharmacokinetic Data: Physiological Models01:15

Model Approaches for Pharmacokinetic Data: Physiological Models

336
Physiological models in pharmacokinetics are instrumental in understanding the distribution and elimination of drugs within the body. These models describe the drug concentration within target organs, influenced by factors such as drug uptake, tissue volume, and blood flow. Drug uptake is governed by the partition coefficient, which signifies the drug concentration ratio in tissue to that in the blood. The blood flow rate to a specific tissue is expressed as Qt, and the rate of change in tissue...
336

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sensitivity of Bayesian Networks to Noise in Their Parameters.

Entropy (Basel, Switzerland)·2024
Same author

Sensitivity of Bayesian Networks to Errors in Their Structure.

Entropy (Basel, Switzerland)·2024
Same author

The SERIES model: Can a standardized approach benefit practitioner evaluation of emergency response systems?

Journal of emergency management (Weston, Mass.)·2021
Same author

Bayesian network models with decision tree analysis for management of childhood malaria in Malawi.

BMC medical informatics and decision making·2021
Same author

Performance Budget Planning: The Case of a Research University.

Computational economics·2020
Same author

Development and Preliminary Feasibility Testing of a Decision Support Tool for Childhood Anxiety Treatment.

Cognitive and behavioral practice·2020
Same journal

Corrigendum to "Estimating bounds on causal effects in high-dimensional and possibly confounded systems" [Int. J. Approx. Reason. 88 (2017) 371-384].

International journal of approximate reasoning : official publication of the North American Fuzzy Information Processing Society·2025
Same journal

<i>n</i>-Dimensional (<i>S</i>,<i>N</i>)-implications.

International journal of approximate reasoning : official publication of the North American Fuzzy Information Processing Society·2020
Same journal

A Bayesian Network Interpretation of the Cox's Proportional Hazard Model.

International journal of approximate reasoning : official publication of the North American Fuzzy Information Processing Society·2019
Same journal

A Constraint Optimization Approach to Causal Discovery from Subsampled Time Series Data.

International journal of approximate reasoning : official publication of the North American Fuzzy Information Processing Society·2018
Same journal

Estimating bounds on causal effects in high-dimensional and possibly confounded systems.

International journal of approximate reasoning : official publication of the North American Fuzzy Information Processing Society·2017
Same journal

Particle MCMC algorithms and architectures for accelerating inference in state-space models.

International journal of approximate reasoning : official publication of the North American Fuzzy Information Processing Society·2017
See all related articles

Related Experiment Video

Updated: Mar 26, 2026

Rodent Estrous Cycle Monitoring Utilizing Vaginal Lavage: No Such Thing As a Normal Cycle
09:05

Rodent Estrous Cycle Monitoring Utilizing Vaginal Lavage: No Such Thing As a Normal Cycle

Published on: August 30, 2021

8.8K

Modeling Women's Menstrual Cycles using PICI Gates in Bayesian Network.

Adam Zagorecki1, Anna Łupińska-Dubicka2, Mark Voortman3

  • 1Operational and Decision Analysis Group, Cranfield University, Defence Academy of the United Kingdom, Shrivenham, SN6 8LA, United Kingdom.

International Journal of Approximate Reasoning : Official Publication of the North American Fuzzy Information Processing Society
|February 3, 2016
PubMed
Summary
This summary is machine-generated.

Probabilistic Independence of Causal Influences (PICI) models reduce Bayesian network complexity. These models offer efficient parameter learning and faster inference, especially for small datasets.

Keywords:
Bayesian networksPICI gatesinferencemodelingparameter learning

More Related Videos

Modeling Breast Cancer in Human Breast Tissue using a Microphysiological System
10:51

Modeling Breast Cancer in Human Breast Tissue using a Microphysiological System

Published on: April 23, 2021

4.7K
A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
10:46

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

11.2K

Related Experiment Videos

Last Updated: Mar 26, 2026

Rodent Estrous Cycle Monitoring Utilizing Vaginal Lavage: No Such Thing As a Normal Cycle
09:05

Rodent Estrous Cycle Monitoring Utilizing Vaginal Lavage: No Such Thing As a Normal Cycle

Published on: August 30, 2021

8.8K
Modeling Breast Cancer in Human Breast Tissue using a Microphysiological System
10:51

Modeling Breast Cancer in Human Breast Tissue using a Microphysiological System

Published on: April 23, 2021

4.7K
A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
10:46

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

11.2K

Area of Science:

  • Artificial Intelligence
  • Machine Learning
  • Probabilistic Graphical Models

Background:

  • Bayesian networks (BNs) face challenges with large conditional probability tables (CPTs) due to exponential growth with parent nodes.
  • Parametric conditional probability distributions offer a solution by reducing parameters linearly with parent nodes.

Purpose of the Study:

  • Introduce a novel class of parametric models: Probabilistic Independence of Causal Influences (PICI) models.
  • Address the challenge of parameter explosion in Bayesian networks.
  • Enhance efficiency in modeling complex interactions and inference.

Main Methods:

  • Developed PICI models, a new class of parametric models for Bayesian networks.
  • Investigated decomposable subsets of PICI models for faster inference.
  • Applied PICI models to learn dynamic BNs for modeling a woman's menstrual cycle.

Main Results:

  • PICI models significantly lower the number of parameters needed for local probability distributions.
  • Decomposable PICI models enable faster inference compared to non-decomposable models.
  • PICI models demonstrate superior parameter accuracy and efficiency for learning from small datasets.

Conclusions:

  • PICI models provide an effective solution for managing parameter complexity in Bayesian networks.
  • The proposed models are particularly beneficial for parameter learning with limited data.
  • PICI models enhance the practical applicability of Bayesian networks in domains like biological cycle modeling.