Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Time-Series Graph00:54

Time-Series Graph

5.2K
A time-series graph is a line graph with repeated measurements taken at successive intervals of time. It is also called a time series chart. To construct a time-series graph, one must look at both pieces of a paired data set. The horizontal axis is used to plot the time increments, and the vertical axis is used to plot the values of the variable that one is measuring. By using the axes in this way, each point on the graph will correspond to time and a measured quantity. The points on the graph...
5.2K
Discrete-Time Fourier Series01:20

Discrete-Time Fourier Series

718
The Discrete-Time Fourier Series (DTFS) is a fundamental concept in signal processing, serving as the discrete-time counterpart to the continuous-time Fourier series. It allows for the representation and analysis of discrete-time periodic signals in terms of their frequency components. Unlike its continuous counterpart, which utilizes integrals, the calculation of DTFS expansion coefficients involves summations due to the discrete nature of the signal.
For a discrete-time periodic signal x[n]...
718
Causality in Epidemiology01:21

Causality in Epidemiology

1.7K
Causality or causation is a fundamental concept in epidemiology, vital for understanding the relationships between various factors and health outcomes. Despite its importance, there's no single, universally accepted definition of causality within the discipline. Drawing from a systematic review, causality in epidemiology encompasses several definitions, including production, necessary and sufficient, sufficient-component, counterfactual, and probabilistic models. Each has its strengths and...
1.7K
Constraints and Statical Determinacy01:26

Constraints and Statical Determinacy

1.0K
In structural engineering, the equilibrium of a system is not only determined by its equations of equilibrium but also with the help of constraints. Constraints refer to restrictions on the motion of a system. The proper combinations of constraints can minimize the total number of constraints needed to maintain a system in mechanical equilibrium. When this happens, the system is said to be statically determinate. For such systems, the unknown reaction supports can be estimated using equilibrium...
1.0K
Model Approaches for Pharmacokinetic Data: Compartment Models01:14

Model Approaches for Pharmacokinetic Data: Compartment Models

573
Compartmental analysis is a widely adopted approach to characterizing drug pharmacokinetics. It uses compartment models that conceptualize the body as a collection of reversibly communicating compartments, each representing a group of tissues exhibiting similar drug distribution characteristics. The movement rate of the drug between these compartments is typically described by first-order kinetics.
Two primary types of compartment models are recognized: mammillary and catenary. The more...
573
Model Approaches for Pharmacokinetic Data: Physiological Models01:15

Model Approaches for Pharmacokinetic Data: Physiological Models

279
Physiological models in pharmacokinetics are instrumental in understanding the distribution and elimination of drugs within the body. These models describe the drug concentration within target organs, influenced by factors such as drug uptake, tissue volume, and blood flow. Drug uptake is governed by the partition coefficient, which signifies the drug concentration ratio in tissue to that in the blood. The blood flow rate to a specific tissue is expressed as Qt, and the rate of change in tissue...
279

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

MindGrab: A Spectrally-Motivated Architecture for Accessible Deep Learning in Neuroimaging.

NeuroImage·2026
Same author

Causal Graphical Models and Their Applications.

Entropy (Basel, Switzerland)·2026
Same author

A century of suicide: Insights from long-term data in the United States.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Deep learning interpretability in neuroimaging: A comprehensive survey and methodological recommendations.

Imaging neuroscience (Cambridge, Mass.)·2026
Same author

Does AI already have human-level intelligence? The evidence is clear.

Nature·2026
Same author

Unsupervised mapping of causal relations between brain lesions and behavior.

bioRxiv : the preprint server for biology·2025
Same journal

Corrigendum to "Estimating bounds on causal effects in high-dimensional and possibly confounded systems" [Int. J. Approx. Reason. 88 (2017) 371-384].

International journal of approximate reasoning : official publication of the North American Fuzzy Information Processing Society·2025
Same journal

<i>n</i>-Dimensional (<i>S</i>,<i>N</i>)-implications.

International journal of approximate reasoning : official publication of the North American Fuzzy Information Processing Society·2020
Same journal

A Bayesian Network Interpretation of the Cox's Proportional Hazard Model.

International journal of approximate reasoning : official publication of the North American Fuzzy Information Processing Society·2019
Same journal

Estimating bounds on causal effects in high-dimensional and possibly confounded systems.

International journal of approximate reasoning : official publication of the North American Fuzzy Information Processing Society·2017
Same journal

Particle MCMC algorithms and architectures for accelerating inference in state-space models.

International journal of approximate reasoning : official publication of the North American Fuzzy Information Processing Society·2017
Same journal

Modeling Women's Menstrual Cycles using PICI Gates in Bayesian Network.

International journal of approximate reasoning : official publication of the North American Fuzzy Information Processing Society·2016
See all related articles

Related Experiment Video

Updated: Feb 10, 2026

Author Spotlight: Alignment of Synchronized Time-Series Data Using the Characterizing Loss of Cell Cycle Synchrony Model for Cross-Experiment Comparisons
07:59

Author Spotlight: Alignment of Synchronized Time-Series Data Using the Characterizing Loss of Cell Cycle Synchrony Model for Cross-Experiment Comparisons

Published on: June 9, 2023

2.0K

A Constraint Optimization Approach to Causal Discovery from Subsampled Time Series Data.

Antti Hyttinen1, Sergey Plis2, Matti Järvisalo1

  • 1HIIT, Department of Computer Science, University of Helsinki.

International Journal of Approximate Reasoning : Official Publication of the North American Fuzzy Information Processing Society
|May 15, 2018
PubMed
Summary
This summary is machine-generated.

This study introduces a novel constraint optimization method for accurately estimating causal structures from time-series data, even when measurements are taken at a slower rate than the system

Keywords:
causal discoverycausalityconstraint optimizationconstraint satisfactiongraphical modelstime series

More Related Videos

Transcranial Magnetic Stimulation for Investigating Causal Brain-behavioral Relationships and their Time Course
11:33

Transcranial Magnetic Stimulation for Investigating Causal Brain-behavioral Relationships and their Time Course

Published on: July 18, 2014

44.0K
Reefshape: A System for the Efficient Collection and Automated Processing of Time-Series Underwater Photogrammetry Data for Benthic Habitat Monitoring
13:35

Reefshape: A System for the Efficient Collection and Automated Processing of Time-Series Underwater Photogrammetry Data for Benthic Habitat Monitoring

Published on: June 13, 2025

1.5K

Related Experiment Videos

Last Updated: Feb 10, 2026

Author Spotlight: Alignment of Synchronized Time-Series Data Using the Characterizing Loss of Cell Cycle Synchrony Model for Cross-Experiment Comparisons
07:59

Author Spotlight: Alignment of Synchronized Time-Series Data Using the Characterizing Loss of Cell Cycle Synchrony Model for Cross-Experiment Comparisons

Published on: June 9, 2023

2.0K
Transcranial Magnetic Stimulation for Investigating Causal Brain-behavioral Relationships and their Time Course
11:33

Transcranial Magnetic Stimulation for Investigating Causal Brain-behavioral Relationships and their Time Course

Published on: July 18, 2014

44.0K
Reefshape: A System for the Efficient Collection and Automated Processing of Time-Series Underwater Photogrammetry Data for Benthic Habitat Monitoring
13:35

Reefshape: A System for the Efficient Collection and Automated Processing of Time-Series Underwater Photogrammetry Data for Benthic Habitat Monitoring

Published on: June 13, 2025

1.5K

Area of Science:

  • Causal inference
  • Time series analysis
  • Machine learning

Background:

  • Subsampling time series data can distort causal structure estimation.
  • Existing methods struggle with accuracy when measurement timescales differ from system timescales.

Purpose of the Study:

  • To develop a robust method for estimating system timescale causal structures from sub-sampled time series data.
  • To improve computational efficiency and accuracy in causal discovery from aggregated time series.

Main Methods:

  • A constraint satisfaction procedure for matching system and measurement timescales.
  • A novel constraint optimization approach for recovering causal structure from finite-sample data.
  • Application to real-world data, robustness and scalability investigations, and solver comparisons.

Main Results:

  • A constraint satisfaction procedure with orders of magnitude better computational performance than prior methods.
  • The first constraint optimization algorithm for recovering system timescale causal structure from sub-sampled data.
  • Demonstrated optimal recovery from statistical errors and successful application to real-world data.

Conclusions:

  • The proposed methods significantly advance the non-parametric estimation of causal structures from sub-sampled time series.
  • The constraint optimization approach offers optimal recovery and handles statistical uncertainties effectively.
  • This work provides a foundation for understanding and addressing challenges in causal discovery from aggregated time series.