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Visuoperceptual sequelae in children with hemophilia and intracranial hemorrhage
Guadalupe Morales1, Esmeralda Matute1, Erin T O'Callaghan1
11 Department of Psychology, CSPP-Alliant International University, Los Angeles, CA, USA ; 2 Neuroscience Institute, University of Guadalajara, Guadalajara, México ; 3 UMAE Hospital de Pediatria CMNO, Medical Research Division, Mexican Institute of Social Security, Guadalajara, México.
Insights
Children with hemophilia and brain bleeds show lower visual perception skills. This impacts identifying objects in challenging situations, suggesting a need for targeted therapies.
Area of Science:
- Neuroscience
- Pediatric Hematology
- Developmental Psychology
Background:
- Focal brain injuries can affect cognitive functions.
- Children with hemophilia are at increased risk for intracranial hemorrhages.
- Understanding these impacts is crucial for early intervention.
Purpose of the Study:
- To investigate the effects of focal brain injuries from intracranial hemorrhages on visual perception and visuospatial abilities.
- To compare these abilities in Mexican children with hemophilia and intracranial hemorrhages (HIC) versus those with hemophilia but no hemorrhage (HH) and healthy controls (CTL).
Main Methods:
- A neuropsychological assessment battery (ENI) was used for analysis.
- Evaluated ten HIC boys, six HH boys, and ten CTL boys.
- Assessed Verbal IQ (VIQ), Performance IQ (PIQ), Full Scale IQ (FSIQ), visual perception, and visuospatial abilities.
Main Results:
- The HIC group scored lower in PIQ and FSIQ compared to the HH group.
- HIC children demonstrated poor performance in visual perception tasks like line orientation, fragmented objects, and overlapping figures.
- Performance deficits were noted in the HIC group relative to matched controls.
Conclusions:
- Impairment in the HIC group is specific to identifying objects under challenging conditions, not general object recognition.
- Findings highlight potential therapeutic and rehabilitative strategies for children with hemophilia and early focal brain lesions.
- Early detection and management of visual processing deficits are important for improving outcomes.
Background:
The goal of this study was to examine the impact of focal brain injuries on the outcomes of visual perception and visuospatial abilities in Mexican children with hemophilia who have experienced intracranial hemorrhages.
Methods:
We assessed ten boys who had hemophilia with intracranial hemorrhage (HIC), six boys who had hemophilia without intracranial hemorrhage (HH), and ten boys without hemophilia (CTL). The Verbal (VIQ), Performance IQs (PIQ), and Full Scale IQs (FSIQ) from the Wechsler Intelligence Scale for Children-Mexican Revision, Visual Perception, and Visuospatial Abilities domains, which are from a neuropsychological assessment battery for Spanish-speaking children (ENI), were employed for our analysis.
Results:
The results showed that the HIC group performed in the low-average range on the PIQ and FSIQ, which was lower than the HH group. The HIC group showed low performance on visual perception tests, such as line orientation, fragmented objects, and overlapping figures, compared with their matched controls.
Conclusions:
The results suggest that it is not the ability to recognize objects that is impaired in the HIC group, but the ability to identify objects under less favorable conditions. Our findings may have therapeutic and rehabilitative implications for the management of children with hemophilia and early focal brain lesions.
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