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Updated: Mar 26, 2026

Author Spotlight: A Novel Approach to Cerebral Ischemia Modeling – Enhancing Reperfusion and Simplifying Procedure
Published on: May 31, 2024
Critical Care of Brain Reperfusion
Shailesh Male1, Chris Nickele2, Lucas Elijovich3,4
1Department of Neurology, University of Tennessee Health Sciences Center, Memphis, TN, USA.
Abstract:
Over the last few decades, the management of acute ischemic stroke has undergone significant advancements with the introduction of intravenous thrombolysis and more recently punctuated by the success of endovascular mechanical thrombectomy trials for large vessel occlusion. These advancements have transformed the practice of neurocritical care. In this review, we present a case-based discussion of common brain reperfusion techniques with an emphasis on complication recognition and management. The article encompasses recent evidence-based recommendations as well as some of our own institutional protocols.

