Related Experiment Video
Updated: Mar 26, 2026

Establishment and Characterization of Small Bowel Neuroendocrine Tumor Spheroids
Published on: October 14, 2019
Gastrointestinal Neuroendocrine Tumors in Two Children
Tugba Koca1, Selim Dereci, Nermin Karahan
1Departments of Pediatrics, Division of Pediatric Gastroenterology, Hepatology and Nutrition, and *Department of Pathology; Faculty of Medicine, Suleyman Demirel University, Isparta, Turkey. Correspondence to: Dr Tugba Koca, Department of Pediatrics, Suleyman Demirel University Faculty of Medicine, Cunur, Isparta, Turkey. tgkoca@gmail.com.
Insights
Childhood neuroendocrine tumors (NETs) and related cell hyperplasia are rare. Early detection is crucial, as a low suspicion index can delay diagnosis of these potentially malignant conditions in pediatric patients.
Area of Science:
- Pediatric Gastroenterology
- Oncology
- Endocrinology
Background:
- Enterochromaffin-like cell hyperplasia and neuroendocrine tumors are uncommon in pediatric populations.
- These conditions can present with nonspecific gastrointestinal symptoms.
Background:
Enterochromaffin-like cell hyperplasia and neuroendocrine tumors are relatively rare in childhood.
Case Characteristics:
A 15-year-old girl who presented with epigastric pain and a 6-year-old boy who was admitted with hematochezia. Endoscopy revealed nodules in the stomach in Case 1, and polyploidy lesion in the rectum in Case 2.
Outcome:
Enterochromaffin-like cell hyperplasia in Case 1 and neuroendocrine tumor in Case 2.
Message:
A low index of suspicion for neuroendocrine tumors in children can result in delay in the detection of these rare but potentially malignant diseases.
More Related Videos
07:39Co-culture of Glutamatergic Neurons and Pediatric High-Grade Glioma Cells Into Microfluidic Devices to Assess Electrical Interactions
Published on: November 17, 2021
08:57Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
Published on: May 17, 2024
Related Concept Videos
Chemotherapy-Induced Nausea and Vomiting: Neurokinin-1 Receptor Antagonists
Gastrointestinal Motility Disorders
Neural Regulation
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption