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Published on: June 24, 2018
The Relationship of Bacterial Biofilms and Capsular Contracture in Breast Implants
Dragana Ajdic1, Yasmina Zoghbi1, David Gerth1
1Dr Ajdic is an Assistant Professor, Department of Dermatology and Cutaneous Surgery, University of Miami, Miller School of Medicine, Miami, FL. Ms Zoghbi is a Medical Student, Dr Gerth is a Volunteer Assistant Professor, Dr Panthaki is a Professor, and Dr Thaller is Chief and a Professor, Division of Plastic, Aesthetic and Reconstructive Surgery, Department of Surgery, University of Miami, Miller School of Medicine, Miami, FL.
Abstract:
Capsular contracture is a common sequelae of implant-based breast augmentation. Despite its prevalence, the etiology of capsular contracture remains controversial. Numerous studies have identified microbial biofilms on various implantable materials, including breast implants. Furthermore, biofilms have been implicated in subclinical infections associated with other surgical implants. In this review, we discuss microbial biofilms as a potential etiology of capsular contracture. The review also outlines the key diagnostic modalities available to identify the possible infectious agents found in biofilm, as well as available preventative and treatment measures.
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