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Imaging Studies for Cardiovascular System III: X-Ray01:20

Imaging Studies for Cardiovascular System III: X-Ray

The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...

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An online x-ray based position validation system for prostate hypofractionated radiotherapy.

Sankar Arumugam1, Mark Sidhom2, Aitang Xing1

  • 1Department of Medical Physics, Liverpool and Macarthur Cancer Therapy Centres and Ingham Institute, New South Wales 2170, Australia.

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This study developed SeedTracker software to verify prostate position during stereotactic body radiation therapy (SBRT) using kV images. The software accurately tracks seed markers, enabling precise monitoring of the isocenter position for improved treatment accuracy.

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Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Image-Guided Therapy

Background:

  • Accurate patient positioning is critical for effective stereotactic body radiation therapy (SBRT).
  • Verifying target volume position during treatment delivery is essential to minimize radiation dose to healthy tissues.
  • Current methods may have limitations in real-time, precise target localization.

Purpose of the Study:

  • To develop and evaluate an in-house software tool, SeedTracker, for verifying target position during SBRT.
  • To assess the software's ability to use kV planar images from an Elekta-Synergy linear accelerator for real-time position verification.
  • To determine the accuracy and reliability of SeedTracker in monitoring prostate position.

Main Methods:

  • Developed SeedTracker software in MATLAB to predict seed positions, autosegment seeds in kV images, and report position shifts.
  • Utilized a humanoid phantom with implanted gold seed markers for performance verification.
  • Evaluated true positive rates for autosegmentation (TPRseg) and triggering alerts (TPRtrig) using static and dynamic positional offsets.

Main Results:

  • SeedTracker achieved 100% TPRseg in most projection angles, with exceptions where anatomy obscured seeds.
  • The system demonstrated an 88% TPRtrig for 3D static offsets, with limitations noted for 2D offsets and specific angle ranges due to monoscopic imaging.
  • Accurate determination of dynamic isocenter trajectories in the superior-inferior direction was achieved.

Conclusions:

  • The developed SeedTracker software accurately autosegments seed positions in kV planar images, providing valuable information for prostate position monitoring.
  • The system's ability to track isocenter trajectories from monoscopic images is beneficial for SBRT.
  • SeedTracker shows significant potential for enhancing treatment delivery accuracy in linac-based SBRT.