Perioperative Adverse Respiratory Events in Overweight/Obese Children: Systematic Review
Insights
Obese children face higher risks of breathing problems during surgery. This review found obesity is linked to hypoxemia and airway issues under general anesthesia.
Area of Science:
- Anesthesiology
- Pediatrics
- Public Health
Background:
- Childhood obesity is a growing concern.
- Obesity is linked to respiratory disorders.
- General anesthesia may worsen respiratory issues in obese children.
Purpose of the Study:
- To systematically review and synthesize literature on the association between childhood obesity and perioperative adverse respiratory events (PAREs).
Main Methods:
- Systematic review of observational studies published between 1990 and 2014.
- Searches conducted in major databases (PubMed, EMBASE, CINAHL, Web of Science, Cochrane).
- Inclusion criteria focused on English-language articles reporting associations between childhood obesity and PAREs.
Main Results:
- Nine studies met the inclusion criteria.
- All included studies reported significant associations between obesity and increased risk of PAREs in pediatric patients.
- Key PAREs identified include hypoxemia, upper airway obstruction, and difficult mask ventilation.
Conclusions:
- Childhood obesity is significantly associated with an increased risk of perioperative adverse respiratory events.
- Healthcare professionals should implement preventive strategies for obese children undergoing anesthesia.
- Further multicenter research is recommended to confirm findings and explore underlying mechanisms.
Abstract:
Childhood obesity is associated with numerous respiratory disorders, which may be aggravated when general anesthesia is administered. This systematic review aimed to investigate and synthesize the published literature on the associations between childhood obesity and perioperative adverse respiratory events (PAREs). By using key terms, observational studies published between 1990 and 2014 in English-language journals indexed by Cumulative Index for Nursing and Allied Health Literature, PubMed, Web of Science, Cochrane Database, and EMBASE were searched for reports of relevant associations. Nine articles were considered eligible for inclusion. In all studies, significant univariate and multivariate associations were reported between obesity and increased risk for PAREs in pediatric patients, mainly for hypoxemia, upper airway obstruction, and difficult mask ventilation. Appropriate strategies for preventing PAREs in obese children need to be followed by health care professionals. Multicenter studies are also recommended for ensuring high generalizability of reported associations and elucidating underlying mechanisms that link obesity to PAREs.
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