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Related Concept Videos

Aging01:26

Aging

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Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
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Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

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Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

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As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
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The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

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Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
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Longitudinal Research02:20

Longitudinal Research

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Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism

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Geriatric patients show significant variation in how their bodies process medications, which can change how effective and safe treatments are. The liver is the primary organ where drug metabolism occurs, involving two main types of chemical reactions: phase I and II. Phase I metabolism is driven by the cytochrome P450 enzyme system, which includes key types such as CYP3A, CYP2D6, and CYP2C9. Research indicates that while aging doesn't notably alter the levels or activity of these enzymes, it...
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Related Experiment Video

Updated: Mar 26, 2026

Getting to Compliance in Forced Exercise in Rodents: A Critical Standard to Evaluate Exercise Impact in Aging-related Disorders and Disease
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Pathways to Advancing Aging Policy-Relevant Research in Academic Settings.

Kathryn G Kietzman1, Lisa M Troy2, Carmen R Green3

  • 1a Center for Health Policy Research and Department of Community Health Sciences, Fielding School of Public Health , University of California-Los Angeles , Los Angeles , California , USA.

Gerontology & Geriatrics Education
|February 6, 2016
PubMed
Summary

Academic institutions face barriers in translating aging research into policy. Scholars, especially minorities, experience marginalization, needing institutional support for policy-relevant research to improve older adult well-being.

Keywords:
aging and diversityaging policycareer advancementfaculty evaluationsfocus groupshigher educationmentoringresearch in aging

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Area of Science:

  • Gerontology
  • Health Policy
  • Sociology of Science

Background:

  • Policy-level changes significantly impact aging populations' health and well-being.
  • A gap exists between scientific knowledge and policy action, with limited focus on academic institutions' role in knowledge generation.
  • Previous research identified knowledge translation barriers, but not specifically within academic settings for aging policy research.

Purpose of the Study:

  • To explore barriers and pathways for developing and maintaining aging policy-relevant research agendas in academic settings.
  • To examine challenges faced by minority group members pursuing aging policy research.
  • To identify strategies for overcoming institutional obstacles in aging policy research.

Main Methods:

  • Exploratory focus group study.
  • In-depth examination of participants' experiences with aging policy-relevant research in academia.
  • Qualitative analysis of barriers, facilitators, and strategies.

Main Results:

  • Scholars face institutional barriers, including limited funding and lower valuation of policy research for tenure and promotion.
  • Minority group participants reported marginalization of their policy research interests.
  • Participants proposed strategies like community collaboration and mentorship to address barriers.

Conclusions:

  • Academic institutions need to reframe the valuation of policy research.
  • Diversifying funding and publishing opportunities can better support aging policy scholars.
  • Addressing institutional barriers is crucial for advancing research that informs policies for aging populations.