Related Experiment Video
Updated: Mar 26, 2026
03:56
A Two-Step Method for Percutaneous Transhepatic Choledochoscopic Lithotomy
Published on: September 13, 2022
3.1K
[Four cases of ceftriaxone-associated biliary pseudolithiasis]
1Department of Surgery, Japanese Red Cross Gifu Hospital.
Summary
Ceftriaxone can cause biliary pseudolithiasis, mimicking gallstones. Conservative management is effective, and checking ceftriaxone history is crucial for diagnosing this condition in patients with abdominal pain.
Area of Science:
- Gastroenterology
- Pharmacology
Background:
- Ceftriaxone is a widely used antibiotic.
- Biliary pseudolithiasis is a rare adverse effect.
- Identifying causative agents is critical for patient management.
Observation:
- Four cases of ceftriaxone-associated biliary pseudolithiasis were observed.
- Patients presented with abdominal pain and imaging findings suggestive of gallstones.
- No invasive procedures like cholecystectomy or ERCP were required.
Findings:
- Conservative treatment was successful in all reported cases.
- Ceftriaxone-induced biliary pseudolithiasis can be managed non-surgically.
- Early recognition of ceftriaxone as a potential cause is key.
Implications:
- Clinicians should consider ceftriaxone-associated biliary pseudolithiasis in patients with unexplained abdominal pain and "gallstones".
- Reviewing antibiotic history, specifically ceftriaxone use, is essential for diagnosis.
- This finding aids in avoiding unnecessary interventions and optimizing patient care.
Related Concept Videos
01:26Endoscopic Procedures V: ERCP
5.5K
Endoscopic Retrograde Cholangiopancreatography (ERCP) is a diagnostic procedure that combines endoscopy and fluoroscopy to diagnose and treat conditions related to the bile ducts, pancreatic ducts, and gallbladder. This procedure is beneficial for identifying and addressing blockages, gallstones, strictures, and tumors within the biliary or pancreatic systems. ERCP is both diagnostic and therapeutic, offering the ability to visualize and treat identified problems in one session.
Patient...
Patient...
5.5K
01:17Chronic Bowel Disorders: Introduction
896
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
896
01:21Drugs for Treatment of Constipation-Predominant IBS
1.2K
Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
1.2K
01:17Hepatic Drug Excretion: Enterohepatic Cycling
3.3K
Enterohepatic cycling involves the active secretion of drugs and their metabolites into the bile via transporters in the canalicular membrane of hepatocytes. This secretion is an integral part of the digestive process, releasing these substances into the gastrointestinal (GI) tract.
Post-release drugs and metabolites can be reabsorbed into the body from the intestine. For conjugated metabolites like glucuronides, reabsorption requires enzymatic hydrolysis by intestinal microflora. This...
Post-release drugs and metabolites can be reabsorbed into the body from the intestine. For conjugated metabolites like glucuronides, reabsorption requires enzymatic hydrolysis by intestinal microflora. This...
3.3K
01:16Hepatic Drug Excretion: Influencing Factors
738
The biliary system of the liver, crucial for bile secretion and drug excretion, comprises intrahepatic bile ducts that merge to form the common hepatic duct. This duct, carrying hepatic bile, combines with the cystic duct, draining the gallbladder and forming the common bile duct, which empties into the duodenum. Bile, produced by hepatic cells lining the bile canaliculi, is composed primarily of water, bile salts, pigments, electrolytes, and lesser amounts of cholesterol and fatty acids. Bile...
738
01:28Pleural Effusion II: Symptoms and Management
1.1K
Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
1.1K