[Brofaromine--a selective, reversible and short-acting MAO-A inhibitor]

During the last years the MAO-inhibitors reached a progressive importance in clinical practice. It was attempted to solve problems of tolerability by a new generation of MAO-inhibitors. Brofaromine is a MAO-inhibitor of the second generation, a selective, reversible and short acting MAO-A-inhibitor, promising that the dangerous "cheese effect" will occur only under extreme conditions. The clinical trials performed hitherto, among other double-blind test versus tranylcypromine and imipramine, demonstrate a good antidepressive efficacy and a good tolerability.