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Updated: Mar 26, 2026

Simultaneous Brightfield, Fluorescence, and Optical Coherence Tomographic Imaging of Contracting Cardiac Trabeculae Ex Vivo
Published on: October 2, 2021
Nanometer resolution optical coherence tomography using broad bandwidth XUV and soft x-ray radiation
Silvio Fuchs1,2, Christian Rödel1,3, Alexander Blinne1
1Institute of Optics and Quantum Electronics, Friedrich-Schiller-University Jena, Jena, Germany.
Extreme ultraviolet coherence tomography (XCT) achieves nanometer-scale resolution for non-invasive imaging, surpassing traditional optical coherence tomography (OCT) limitations. This breakthrough enables detailed subsurface imaging of nanostructures with unprecedented precision.
Area of Science:
- Physics
- Materials Science
- Nanotechnology
Background:
- Optical coherence tomography (OCT) offers non-invasive cross-sectional imaging, valuable for deep or fast-moving samples.
- Conventional OCT, using infrared and optical wavelengths, has an axial resolution limited to approximately 1 micrometer.
- Existing limitations hinder detailed imaging of nanometer-scale structures.
Purpose of the Study:
- Introduce extreme ultraviolet coherence tomography (XCT) as a novel non-invasive imaging technique.
- Demonstrate XCT's capability for imaging nanometer structures with enhanced axial resolution.
- Explore XCT's potential for semiconductor metrology and water window imaging.
Main Methods:
- Utilized extreme ultraviolet (EUV) light sources with nanometer-scale coherence lengths.
- Exploited spectral transmission windows of materials like silicon.
- Performed tomographic imaging of buried nanostructures and nanometer-scale layers.
Main Results:
- Achieved axial resolution in coherence tomography improved from micrometers to a few nanometers.
- Demonstrated tomographic imaging of buried nanostructures with axial resolution better than 18 nm.
- Resolved nanometer-scale platinum layers with resolution better than 8 nm using water window wavelengths.
Conclusions:
- XCT significantly enhances axial resolution for non-invasive cross-sectional imaging.
- XCT provides nanometer-scale precision for subsurface imaging of nanostructures.
- XCT shows strong potential for advanced semiconductor metrology and specialized imaging applications.
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