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Characterization of a new HLA-A allele, HLA-A*02:07:08, by cloning and sequencing
W Y Wang1, W Zhang2,3, L X Li1,4
1Immunogenetics Research Group, Department of Immunology, College of Basic Medical Sciences, Central South University, Changsha, China.
International Journal of Immunogenetics
|February 11, 2016
Abstract:
In this report, we present a novel HLA-A*02:07 allele, HLA-A*02:07:08. HLA-A*02:07:08 was identified in an individual of Han ethnicity in Hunan province, southern China. Following polymerase chain reaction-sequence-based typing (PCR-SBT), this new allele was further confirmed by cloning and sequencing. HLA-A*02:07:08 differs from HLA-A*02:07:01 by a single synonymous C to T substitution at nucleotide position 131 in exon 3.
