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Alcohol Lowers Your (Intestinal) Inhibitions
Namrata Iyer1, Shipra Vaishnava1
1Molecular Microbiology and Immunology Department, Brown University, Providence, RI 02912, USA.
Abstract:
Alcohol causes microbiota dysbiosis and breaches intestinal integrity, resulting in liver inflammation and ultimately cirrhosis. In this issue of Cell Host & Microbe, Wang et al. (2016) demonstrate that ethanol suppresses the intestinal anti-microbial response. This enables gut bacteria to trespass to the liver and thus exacerbates the disease progression.
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