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Production and interconversion of 1,2-propanediol and hydroxyacetone by Escherichia coli

F Commodari¹, B K Hunter

¹Department of Chemistry, Queen's University, Kingston, Ont., Canada.

Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire

|August 1, 1989

Abstract:

The anaerobic metabolism of marginally lethal levels of [13C]formaldehyde by Escherichia coli (K12, MU352, CRB, and CR63) was followed in vivo by 13C NMR. The products include 1,2-propanediol. Under aeration, the 1,2-propanediol is converted to hydroxyacetone. The hydroxyacetone is reconverted to 1,2-propanediol when aeration is stopped. The process can be cycled by varying the rate of aeration.

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