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Updated: Mar 25, 2026

Three-Dimensional Imaging of the Vertebral Lymphatic Vasculature and Drainage using iDISCO+ and Light Sheet Fluorescence Microscopy
Published on: May 22, 2020
The "Hyperdense Paraspinal Vein" Sign: A Marker of CSF-Venous Fistula
P G Kranz1, T J Amrhein2, W I Schievink3
1From the Departments of Radiology (P.G.K., T.J.A., L.G.) peter.kranz@duke.edu.
Abstract:
CSF-venous fistula is a recently reported cause of spontaneous intracranial hypotension that may occur in the absence of myelographic evidence of CSF leak. Information about this entity is currently very limited, but it is of potential importance given the large percentage of cases of spontaneous intracranial hypotension associated with negative myelography findings. We report 3 additional cases of CSF-venous fistula and describe the "hyperdense paraspinal vein" sign, which may aid in its detection.
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