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Related Experiment Videos

Pharmaco-epidemiological perspectives.

U Bergman1

  • 1Department of Clinical Pharmacology, Karolinska Institute, Huddinge University Hospital, Sweden.

Pharmaceutisch Weekblad. Scientific Edition
|October 20, 1989
PubMed
Summary
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Large-scale pharmaco-epidemiological studies using electronic health data are advancing drug safety surveillance. North America

Area of Science:

  • Pharmacoepidemiology
  • Public Health
  • Health Informatics

Background:

  • Growing concerns regarding drug safety have increased the demand for robust drug surveillance methods.
  • Computerized health care data enables the creation of large populations for epidemiological research.

Purpose of the Study:

  • To highlight the growing importance of pharmacoepidemiology and its application in drug safety surveillance.
  • To emphasize the utility of large computerized health databases for drug evaluation.

Main Methods:

  • Utilizing computerized pharmacy or billing records to link drug exposure with diagnostic information.
  • Employing record-linkage systems to establish objective drug histories for cohort and case-control studies.

Main Results:

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  • Large databases in North America are routinely used for extensive pharmaco-epidemiological studies.
  • These studies facilitate the discovery of novel drug-disease associations.

Conclusions:

  • North American findings on drug-disease associations may have significant implications for European populations.
  • The European community requires a strategic approach to effectively respond to these international drug safety findings.