Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Tuberculosis skin testing and preventive therapy.

C A Hanson1, L B Reichman

  • 1Department of Medicine, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark.

Seminars in Respiratory Infections
|September 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Michael Dee Iseman, MD - the passing of a legend.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2023
Same author

European LeukemiaNet-defined primary refractory acute myeloid leukemia: the value of allogeneic hematopoietic stem cell transplant and overall response.

Blood cancer journal·2022
Same author

Extramedullary hematopoiesis in the absence of myeloproliferative neoplasm: Mayo Clinic case series of 309 patients.

Blood cancer journal·2018
Same author

Risk factors for arterial versus venous thrombosis in polycythemia vera: a single center experience in 587 patients.

Blood cancer journal·2017
Same author

Prognostic significance of ASXL1 mutation types and allele burden in myelofibrosis.

Leukemia·2017
Same author

Application of current prognostic models for primary myelofibrosis in the setting of post-polycythemia vera or post-essential thrombocythemia myelofibrosis.

Leukemia·2017
Same journal

TB vaccines at the turn of the century: insights into immunity to M. tuberculosis and modern approaches for prevention of an ancient disease.

Seminars in respiratory infections·2003
Same journal

Environmental infection control of tuberculosis.

Seminars in respiratory infections·2003
Same journal

Mycobacterium tuberculosis: the treatment of active disease.

Seminars in respiratory infections·2003
Same journal

Pediatric tuberculosis.

Seminars in respiratory infections·2003
Same journal

Clinical and radiographic features of HIV-related tuberculosis.

Seminars in respiratory infections·2003
Same journal

Treatment of latent tuberculosis infection.

Seminars in respiratory infections·2003
See all related articles

Tuberculin skin testing effectively detects tuberculosis infection, especially in close contacts. Preventive therapy is crucial for individuals with positive tests to prevent disease progression and eliminate TB.

Area of Science:

  • Public Health
  • Infectious Disease Epidemiology
  • Immunology

Background:

  • Tuberculin skin testing (TST) is a key diagnostic tool for identifying tuberculosis (TB) infection.
  • TST can yield false-negative results in immunocompromised individuals, including those with HIV, on immunosuppressants, malnourished, or elderly.
  • Despite limitations, TST remains valuable for detecting TB infection in high-risk populations and close contacts.

Purpose of the Study:

  • To highlight the utility of TST in TB infection detection.
  • To outline the indications for preventive therapy following a reactive TST.
  • To emphasize the importance of preventive therapy in TB elimination strategies.

Main Methods:

  • Review of TST utility in detecting latent tuberculosis infection.

Related Experiment Videos

  • Identification of patient groups requiring further evaluation after reactive TST.
  • Criteria for initiating isoniazid preventive therapy (IPT) for individuals with reactive TST.

    • Main Results:

    • Reactive TST necessitates further investigation to exclude active TB disease.
    • IPT is recommended for specific high-risk groups with reactive TST, including close contacts, recent converters, and those under 35.
    • Ongoing research explores shorter treatment regimens for TB prophylaxis.

    Conclusions:

    • TST is a reliable method for identifying individuals with TB infection.
    • Prompt initiation of preventive therapy for eligible individuals is essential for TB control.
    • Widespread recognition and implementation of preventive therapy are vital for TB elimination.