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Updated: Mar 25, 2026

Saline Lavage for Sampling of the Canine Nasal Immune Microenvironment
Published on: December 27, 2024
Canine Staphylococcus pseudintermedius sinonasal infection in human hosts.
Edward C Kuan1, Alexander J Yoon1, Tara Vijayan2
1Department of Head and Neck Surgery, University of California, Los Angeles (UCLA), Los Angeles, CA.
Staphylococcus pseudintermedius, a bacteria common in dogs, can cause chronic rhinosinusitis (CRS) in humans. Culture-directed therapy successfully treated four refractory CRS cases in dog owners, highlighting the importance of considering zoonotic pathogens.
Area of Science:
- Medical Microbiology
- Infectious Diseases
- Otolaryngology
Background:
- Staphylococcus pseudintermedius is a common bacterium in canine skin and nasal flora.
- This bacterium can act as an opportunistic pathogen in dogs and colonize human nasal passages.
- Chronic rhinosinusitis (CRS) can be refractory to standard medical treatments.
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