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Hypersensitivity reactions to human seminal plasma.
1Division of Allergy and Immunology, St. Louis University School of Medicine, Missouri.
Annals of Allergy
|December 1, 1989
Summary
Human seminal plasma hypersensitivity is a rare allergic reaction primarily affecting young women. Treatment options include immunotherapy and topical cromolyn for symptom prevention.
Area of Science:
- Reproductive immunology
- Allergy and immunology
Background:
- Human seminal plasma hypersensitivity is a rare but serious allergic reaction.
- It predominantly affects young women, potentially due to altered immune status in reproductive organs.
- Patients often have a history of atopy, with tests confirming a reaginic humoral mechanism.
Purpose of the Study:
- To describe the characteristics of human seminal plasma hypersensitivity.
- To explore potential treatment and prevention strategies.
Main Methods:
- Clinical case description and review of immunologic tests.
- Evaluation of treatment outcomes for immunotherapy and topical cromolyn.
Main Results:
- Immunologic tests typically corroborate a reaginic humoral mechanism.
- Selected patients show successful treatment outcomes with selective immunotherapy.
- Topical cromolyn shows promise for symptom prevention.
Conclusions:
- Human seminal plasma hypersensitivity is a distinct allergic condition.
- Selective immunotherapy and topical cromolyn are promising therapeutic options.