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Updated: Mar 25, 2026
Human Blastocyst Biopsy and Vitrification
Published on: July 26, 2019
Vitrified/warmed single blastocyst transfer in preimplantation genetic diagnosis/preimplantation genetic screening
Jin Huang1, Rong Li1, Ying Lian1
1Department of Obstetrics and Gynecology, Reproductive Medical Centre, Peking University Third HospitalBeijing 100191, China; Key Laboratory of Assisted Reproduction, Ministry of Education and Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive TechnologyBeijing 100191, China.
Objective:
To investigate the single blastocyst transfer in preimplantation genetic diagnosis (PGD)/preimplantation genetic screening (PGS) cycles.
Methods:
80 PGD/PGS cycles undergoing blastocyst biopsy were studied. There were 88 warming cycles during the study period. Only one warmed blastocyst was transferred per cycle. The outcomes were followed up to the infants were born.
Results:
The embryo implantation rate was 54.55% (48/88). The clinical pregnancy rate was 54.55% (48/88) per transfer cycle and 60% (48/80) per initial PGD/PGS cycle. There was no multi-pregnant in this study. The live birth rate was 42.05% (37/88) per transfer cycle and 46.25% (37/80) per initial PGD/PGS cycle.
Conclusion:
In PGD/PGS cycles, single blastocyst transfer reduces the multiple pregnancy rate without affecting the clinical outcomes.
