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Tissue Transplantation

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...

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Related Experiment Video

Updated: Mar 25, 2026

Surgical Approach, Challenges, and Resolutions for Uterus Transplantation in Rats

Surgical Approach, Challenges, and Resolutions for Uterus Transplantation in Rats

Published on: April 14, 2023

Human uterus transplantation in focus.

Pernilla Dahm-Kähler¹, Cesar Diaz-Garcia², Mats Brännström³

¹Department of Obstetrics and Gynecology, Sahlgrenska Academy, University of Gothenburg, 41345 Gothenburg, Sweden.

British Medical Bulletin

|February 19, 2016

Summary

Uterus transplantation (UTx) offers hope for women with absolute uterine factor infertility (AUFI). Live donor UTx has resulted in live births, establishing it as a viable treatment option.

Keywords:

infertility transplantation uterus

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Last Updated: Mar 25, 2026

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Utero-tubal Embryo Transfer and Vasectomy in the Mouse Model

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Published on: February 28, 2014

Area of Science:

Reproductive medicine
Transplantation surgery

Background:

Absolute uterine factor infertility (AUFI) affects approximately 1 in 500 women of reproductive age.
Uterus transplantation (UTx) is emerging as a primary treatment for AUFI.

Purpose of the Study:

To review potential candidates, research, and human uterus transplantation (UTx) cases.
To discuss the current landscape and future directions of UTx for AUFI.

Main Methods:

Systematic review of published articles.
Inclusion of the authors' research experience.

Main Results:

The first live births from UTx in 2014 confirmed its potential for treating AUFI.
Fifteen years of systematic research preceded these successful outcomes.

Conclusions:

Ongoing human UTx trials are crucial for gathering data on risks, effectiveness, and long-term outcomes for all involved.
Future UTx research should prioritize prospective observational studies and international data registries to ensure comprehensive data collection on quality of life and child development.