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Updated: Mar 25, 2026
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Aseptic Laboratory Techniques: Volume Transfers with Serological Pipettes and Micropipettors
Published on: May 31, 2012
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Comparison of Aseptic Compounding Errors Before and After Modified Laboratory and Introductory Pharmacy Practice
Vincent C Dennis1, Arthur H Owora1, Alice E Kirkpatrick2
1University of Oklahoma College of Pharmacy, Oklahoma City, Oklahoma.
American Journal of Pharmaceutical Education
|February 19, 2016
Summary
Pharmacy students made fewer aseptic compounding errors after curriculum changes. Early laboratory and introductory practice experiences improved aseptic technique in the third professional year.
Area of Science:
- Pharmacy education
- Pharmaceutical compounding
Background:
- Aseptic compounding is critical for patient safety.
- Pharmacy curricula aim to minimize compounding errors.
Purpose of the Study:
- To evaluate the impact of revised pharmacy practice laboratories and an introductory pharmacy practice experience (IPPE) on aseptic compounding errors.
- To determine if these changes reduced errors by the end of the third professional year.
Main Methods:
- Aseptic compounding labs were moved to the second year.
- An 80-hour institutional IPPE was added between the second and third years.
- Instructor assessments using a grading checklist evaluated errors in second- and third-year students before and after changes.
Main Results:
- Third-year students committed fewer aseptic technique errors compared to their second-year performance.
- Error rates were significantly lower for students on the Oklahoma City campus.
- Major aseptic technique errors significantly decreased for two consecutive third-year cohorts post-curriculum modification.
Conclusions:
- Integrating aseptic compounding labs earlier and adding an institutional IPPE effectively reduced instructor-assessed errors.
- Curricular adjustments enhance aseptic technique proficiency in pharmacy students.
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