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Daily rhythmicity of high affinity copper transport
Ana Perea-García1, Amparo Sanz2, Joaquín Moreno1
1a Departament de Bioquímica i Biologia Molecular, Universitat de Valéencia , Burjassot , Valencia , Spain.
Plant Signaling & Behavior
|February 19, 2016
Summary
Plants dynamically regulate copper (Cu) uptake using light and internal clocks. This ensures essential cupro-proteins function efficiently, especially when copper is scarce, optimizing plant growth.
Area of Science:
- Plant Physiology
- Molecular Biology
- Biochemistry
Background:
- Copper (Cu) is essential for cupro-proteins in mitochondrial and chloroplast electron transport chains.
- Daily light/dark cycles create differential Cu demand, requiring precise spatiotemporal regulation.
- Cu scarcity necessitates efficient import via high-affinity Cu transporters (COPTs).
Purpose of the Study:
- To model the temporal regulation of copper homeostasis in plants.
- To investigate the role of the SPL7 transcription factor in copper acquisition.
- To understand how copper availability integrates with circadian clock components.
Main Methods:
- Analysis of light- and clock-responsive cis elements in gene promoters.
- Modeling the synchrony between SPL7 oscillatory patterns and COPT targets.
- Investigating the feedback mechanisms of copper on gene regulation.
- Assessing the impact of exogenous copper on circadian clock components.
Main Results:
- A model demonstrates synchrony between SPL7 and its target COPT2, regulating copper uptake.
- Copper availability influences SPL7-dependent regulation of COPT transporters.
- Exogenous copper affects circadian clock components, including GIGANTEA transcript abundance.
Conclusions:
- Plants exhibit a dynamic, diurnal response to copper availability.
- This integrated response optimizes metabolic efficiency under challenging growth conditions.
- Copper homeostasis is tightly linked to light/dark cycles and circadian rhythms.
Keywords:
Arabidopsis thalianacircadian clockcopper deficiencycopper transportdiurnal rhythmheavy metalsMore Related Videos
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