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Related Concept Videos

Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

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Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
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Pulmonary Tuberculosis I01:29

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Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
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Pulmonary Tuberculosis III01:31

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Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
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Pulmonary Tuberculosis V01:28

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Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
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Pulmonary Tuberculosis IV01:26

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Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
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Atypical Pneumonia01:14

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Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease...
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Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
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Crescentic Glomerulonephritis Associated with Pulmonary Tuberculosis.

K V Kanodia1, A V Vanikar2, R D Patel1

  • 1Professor, Department of Pathology, Laboratory Medicine, Transfusion Services and Immunohematology, G.R. Doshi and K.M. Mehta Institute of Kidney Diseases & Research Centre and Dr. H.L. Trivedi Institute of Transplantation Sciences , Civil Hospital Campus, Asarwa, Ahmedabad, India .

Journal of Clinical and Diagnostic Research : JCDR
|February 20, 2016
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Summary

Tuberculosis can rarely affect the kidneys, causing rapidly progressive glomerulonephritis. This case highlights a rare presentation of kidney tuberculosis and its challenging treatment in a young man.

Keywords:
Acid-resistant bacilliAnti-tuberculous drugImmunofluorescence

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Area of Science:

  • Nephrology
  • Infectious Diseases
  • Pathology

Background:

  • Tuberculosis of the kidney and urinary tract is caused by Mycobacterium tuberculosis complex.
  • Renal infection typically occurs via hematogenous spread from a pulmonary focus.
  • Glomerular involvement presenting as rapidly progressive glomerulonephritis is a rare manifestation of tuberculosis.

Observation:

  • A 26-year-old man presented with crescentic glomerulonephritis and pulmonary tuberculosis.
  • The patient underwent treatment with corticosteroids, hemodialysis, intravenous immunoglobulin, and plasmapheresis.
  • Initial anti-tuberculosis treatment for renal pathology was ineffective.

Findings:

  • The patient required maintenance hemodialysis due to lack of response to anti-tuberculosis therapy for the renal disease.
  • Pulmonary tuberculosis showed a positive response to treatment.
  • This case illustrates a rare association between pulmonary tuberculosis and crescentic glomerulonephritis.

Implications:

  • Highlights the diagnostic and therapeutic challenges of renal tuberculosis presenting as glomerulonephritis.
  • Suggests that renal tuberculosis should be considered in patients with unexplained rapidly progressive glomerulonephritis, especially in endemic areas.
  • Emphasizes the need for tailored treatment strategies for renal tuberculosis-associated glomerulonephritis.