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Averting the Legacy of Kidney Disease--Focus on Childhood

Julie R Ingelfinger1, Kamyar Kalantar-Zadeh, Franz Schaefer

  • 1Department of Pediatrics, Harvard Medical School, Boston, Mass., USA.

American Journal of Nephrology
|February 20, 2016
PubMed

Insights

Childhood kidney disease, often stemming from congenital issues, can predict adult kidney problems. Early detection and treatment are crucial for better outcomes, even in advanced cases.

Area of Science:

  • Pediatric Nephrology
  • Public Health

Background:

  • World Kidney Day 2016 highlights childhood kidney disease and its links to adult conditions.
  • Congenital anomalies and inherited disorders are primary causes in children, unlike adults where glomerulopathies and diabetes are more common.

Discussion:

  • Acute kidney injury in children can lead to long-term hypertension and chronic kidney disease (CKD).
  • Premature birth and low birth weight increase the risk of developing CKD later in life.
  • Close monitoring of high-risk children can enable early detection and effective prevention or treatment of kidney disease.

Key Insights:

  • Advanced childhood CKD is treatable, with children often responding better to kidney replacement therapy than adults.
  • A small percentage of children with CKD require intensive interventions like dialysis or transplantation.

Outlook:

  • Addressing healthcare access disparities is vital to ensure effective treatment for all children with kidney disease, regardless of location or economic status.
  • Raising public, policymaker, and caregiver awareness is essential for improving childhood kidney disease management.

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