Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Fixation and Sectioning01:03

Fixation and Sectioning

8.8K
Two basic types of preparation are used to visualize specimens with a light microscope: wet mounts and fixed specimens.
The simplest type of preparation is the wet mount, in which the specimen is placed in a drop of liquid on the slide. A liquid specimen can be directly deposited on the slide using a dropper. Solid specimens, such as skin scraping, can be placed on the slide before adding a drop of liquid to prepare the wet mount. Sometimes the liquid is simply water, but stains are often added...
8.8K
Overview of Microscopy Techniques01:22

Overview of Microscopy Techniques

17.7K
The early pioneers of microscopy opened a window into the invisible world of microorganisms. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes that leveraged nonvisible light, such as fluorescence microscopy that uses an ultraviolet light source and electron microscopy that uses short-wavelength electron beams. These advances significantly improved magnification, image resolution, and contrast. By comparison, the...
17.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of a national mesothelioma network on outcomes including survival.

Thorax·2026
Same author

Secondary extraocular extension of choroidal melanoma following primary photodynamic therapy.

Eye (London, England)·2026
Same author

Modeling Genetic Risk of β-Cell Dysfunction in Human Induced Pluripotent Stem Cells From Patients Carrying the MTNR1B Risk Variant.

Journal of pineal research·2025
Same author

In Response to: Reflections on ECPR in New Zealand: Past, Present and Future.

Emergency medicine Australasia : EMA·2025
Same author

Deletion of Hsd11b1 suppresses caloric restriction-induced bone marrow adiposity in male but not female mice.

The Journal of endocrinology·2024
Same author

Ocular Lichen Planus: A clinicopathologic review.

European journal of ophthalmology·2024

Related Experiment Video

Updated: Mar 25, 2026

Grossing of Non-neoplastic Globes, Including Fetal Eyes
05:15

Grossing of Non-neoplastic Globes, Including Fetal Eyes

Published on: May 30, 2025

680

Macroscopic techniques for ophthalmic tumor specimens.

Fiona Roberts1

  • 1Department of Pathology, Queen Elizabeth University Hospital, Govan Rd, Glasgow G51 4 TF, United Kingdom.

Seminars in Diagnostic Pathology
|February 21, 2016
PubMed
Summary
This summary is machine-generated.

This guide details handling various ocular tumor specimens in ophthalmic pathology, from complex enucleations to smaller eyelid and corneal samples, ensuring accurate histology and molecular studies.

Keywords:
EndoresectionEnucleationExenterationExoresectionMelanomaRetinoblastoma

More Related Videos

Fluorescence Microscopy for ATP Internalization Mediated by Macropinocytosis in Human Tumor Cells and Tumor-xenografted Mice
08:31

Fluorescence Microscopy for ATP Internalization Mediated by Macropinocytosis in Human Tumor Cells and Tumor-xenografted Mice

Published on: June 30, 2021

3.2K
Correlative Light- and Electron Microscopy Using Quantum Dot Nanoparticles
11:16

Correlative Light- and Electron Microscopy Using Quantum Dot Nanoparticles

Published on: August 7, 2016

10.3K

Related Experiment Videos

Last Updated: Mar 25, 2026

Grossing of Non-neoplastic Globes, Including Fetal Eyes
05:15

Grossing of Non-neoplastic Globes, Including Fetal Eyes

Published on: May 30, 2025

680
Fluorescence Microscopy for ATP Internalization Mediated by Macropinocytosis in Human Tumor Cells and Tumor-xenografted Mice
08:31

Fluorescence Microscopy for ATP Internalization Mediated by Macropinocytosis in Human Tumor Cells and Tumor-xenografted Mice

Published on: June 30, 2021

3.2K
Correlative Light- and Electron Microscopy Using Quantum Dot Nanoparticles
11:16

Correlative Light- and Electron Microscopy Using Quantum Dot Nanoparticles

Published on: August 7, 2016

10.3K

Area of Science:

  • Ophthalmic Pathology
  • Surgical Pathology
  • Oncology

Background:

  • Accurate histopathological analysis of ocular tumors is critical for diagnosis and treatment planning.
  • Proper specimen handling is essential for preserving tissue integrity for subsequent analyses.

Purpose of the Study:

  • To provide comprehensive guidelines for handling diverse ocular tumor specimens submitted to ophthalmic pathology.
  • To emphasize the importance of anatomical knowledge and clinical information in specimen processing.
  • To outline recommendations for tissue handling for molecular studies.

Main Methods:

  • Description of techniques for handling enucleation and exenteration specimens.
  • Guidance on processing smaller specimens like eyelid, conjunctival, and corneal biopsies.
  • Emphasis on correlating anatomical structures with histological sectioning.

Main Results:

  • Detailed protocols for managing various types of ocular specimens.
  • Highlighting the link between meticulous handling, appropriate block selection, and clinically relevant pathology reports.
  • Strategies for preserving tissue for advanced molecular investigations.

Conclusions:

  • Effective management of ocular tumor specimens requires specialized knowledge of ocular anatomy and detailed clinical data.
  • Adherence to recommended handling procedures ensures optimal diagnostic yield and facilitates molecular testing.
  • This approach enhances the quality of ophthalmic pathology reports and patient care.