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Published on: February 14, 2022
Pediatric Thoracic Organ Transplantation: Current Indications, Techniques, and Imaging Findings
Patricia T Chang1, Jamie Frost1, A Luana Stanescu2
1Department of Radiology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.
Insights
Pediatric lung and heart transplants are effective treatments for end-stage heart and lung disease. This review covers unique imaging challenges and complications in pediatric thoracic organ transplantation.
Area of Science:
- Cardiology
- Pulmonology
- Pediatric Surgery
- Medical Imaging
Background:
- Pediatric lung and heart transplantation have advanced significantly in the last decade.
- Improved surgical techniques and immunosuppression knowledge have made these procedures viable therapeutic options.
- These transplants address end-stage cardiopulmonary disease in children with congenital and acquired disorders.
Purpose of the Study:
- To provide an updated review of pediatric lung and heart transplantation.
- To highlight the unique preoperative and postoperative imaging evaluation challenges in this patient group.
- To discuss postoperative transplant anatomy, imaging techniques, and potential complications.
Main Methods:
- Literature review of recent advancements in pediatric thoracic organ transplantation.
- Analysis of imaging techniques used in preoperative and postoperative evaluation.
- Compilation of common complications and their imaging findings.
Main Results:
- Pediatric thoracic organ transplantation outcomes are comparable to adult outcomes.
- Unique challenges exist in imaging pediatric transplant recipients.
- Postoperative imaging is crucial for monitoring transplant anatomy and detecting complications.
Conclusions:
- Pediatric lung and heart transplantation are established treatments for severe cardiopulmonary disease.
- Specialized imaging approaches are necessary for evaluating pediatric thoracic organ transplants.
- Understanding transplant anatomy and potential complications through imaging is vital for patient management.
Abstract:
In the past decade, with improved surgical technique and knowledge of immunosuppression, pediatric lung and heart transplantation have been established as viable therapeutic interventions for pediatric patients with end-stage cardiopulmonary disease from various underlying congenital and acquired disorders. Although outcomes for pediatric patients are similar to those for adult patients, thoracic organ transplantation in this special age group carries unique challenges for preoperative and postoperative imaging evaluation. The article provides an up-to-date review of the postoperative transplant anatomy, imaging techniques, and complications of pediatric lung and heart transplantation.
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