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Related Experiment Video

Updated: Mar 25, 2026

Laparoscopic Non-Mesh Cerclage Pectopexy for Pelvic Organ Prolapse
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Transabdominal cerclage: preconceptual versus first trimester insertion.

Feroza Dawood1, Roy Gibb Farquharson2

  • 1Department of Obstetrics and Gynaecology, Liverpool Women's Hospital, Crown Street, Liverpool L8 7SS, United Kingdom.

European Journal of Obstetrics, Gynecology, and Reproductive Biology
|February 21, 2016
PubMed
Summary
This summary is machine-generated.

Preconceptual transabdominal cerclage (TAC) offers better outcomes than first-trimester TAC for preventing mid-trimester loss and preterm birth. This approach also reduces surgical complications and pregnancy-related morbidity.

Keywords:
Pre-term labourSpontaneous mid-trimester lossesTransabdominal cerclageTransvaginal cerclage

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Area of Science:

  • Maternal-Fetal Medicine
  • Surgical Obstetrics

Background:

  • Transabdominal cerclage (TAC) is a critical intervention for preventing recurrent pregnancy loss, particularly after transvaginal cerclage failure.
  • TAC can be performed either preconceptually or during the first trimester of pregnancy.

Purpose of the Study:

  • To compare the efficacy and safety of preconceptual transabdominal cerclage (PC-TAC) versus first-trimester transabdominal cerclage (T1-TAC).
  • To evaluate differences in surgical and pregnancy-related morbidity and subsequent pregnancy outcomes between PC-TAC and T1-TAC.

Main Methods:

  • A 22-year retrospective and prospective cohort study involving 161 women with a history of mid-trimester loss and failed transvaginal cerclage.
  • Participants were divided into preconceptual (PC) TAC and first-trimester (T1) TAC groups.
  • Inclusion criteria included screening for antiphospholipid syndrome and bacterial vaginosis.

Main Results:

  • Preconceptual TAC demonstrated higher success rates for pregnancies >24 weeks (97% vs. 93%) and >34 weeks (90% vs. 74%).
  • The PC-TAC group experienced significantly fewer emergency cesarean sections for preterm delivery (12% vs. 36%).
  • No surgical complications were reported in the PC-TAC group, compared to 5% in the T1-TAC group, with significantly less hemorrhage (>500ml) in the PC-TAC group (50% in T1-TAC).

Conclusions:

  • Preconceptual transabdominal cerclage is more effective in preventing recurrent mid-trimester loss and preterm labor compared to first-trimester TAC.
  • PC-TAC is associated with reduced surgical and pregnancy-related morbidity.