Carotid Stenosis in Cardiac Surgery-No Difference in Postoperative Outcomes
Molly Schultheis1, Siavash Saadat1, Victor Dombrovskiy2
1Department of Cardiothoracic Surgery, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, United States.
Insights
Patients with asymptomatic carotid stenosis undergoing cardiac surgery do not face increased risks of mortality or complications. Prophylactic carotid revascularization may not be necessary for these individuals.
Area of Science:
- Cardiovascular Surgery
- Neurology
- Vascular Surgery
Background:
- The necessity of revascularizing asymptomatic carotid stenosis prior to cardiac surgery remains a subject of debate.
- This study investigates cardiac surgery outcomes in patients with asymptomatic carotid stenosis.
Purpose of the Study:
- To evaluate the impact of asymptomatic carotid stenosis on postoperative complications and mortality in patients undergoing cardiac surgery.
- To determine if prophylactic carotid revascularization is indicated for patients with asymptomatic carotid stenosis before cardiac surgery.
Main Methods:
- A retrospective analysis of 1,781 cardiac surgery patients from January 2012 to June 2013.
- Preoperative carotid duplex screening was performed on 1,357 patients.
- Data on demographics, comorbidities, stenosis degree, complications, and mortality were collected and analyzed using chi-square tests and logistic regression.
Main Results:
- Asymptomatic carotid stenosis was identified in 29.7% of patients (355 moderate, 48 severe).
- Patients with stenosis were older and more likely to be female, but no significant differences in mortality or complications (stroke, TIA) were observed compared to those without stenosis.
- Multivariable analysis confirmed that carotid stenosis did not significantly impact postoperative mortality or stroke development.
Conclusions:
- Asymptomatic carotid stenosis does not appear to increase the risk of adverse outcomes after cardiac surgery.
- Prophylactic carotid revascularization may not be routinely indicated for patients with asymptomatic carotid stenosis undergoing cardiac surgery.
Background:
Debate over revascularization of asymptomatic carotid stenosis before cardiac surgery is ongoing. In this study, we analyze cardiac surgery outcomes in patients with asymptomatic carotid stenosis at a single hospital.
Methods:
In this study, 1,781 patients underwent cardiac surgery from January 2012 to June 2013; 1,357 with preoperative screening carotid duplex were included. Patient demographics, comorbidities, degree of stenosis, postoperative complications, and mortality were evaluated. Chi-square test and logistic regression analysis were performed.
Results:
Asymptomatic stenosis was found in 403/1,357 patients (29.7%; 355 moderate and 48 severe). Patients with stenosis, compared with those without, were older (71.7 ± 11 vs. 66.3 ± 12 years; p < 0.01). Females were more likely to have stenosis (odd ratio, = 1.7; 95% confidence interval, 1.4-2.2); however, patients were predominantly male in both groups. There were no significant differences in the rates of mortality and postoperative complications, including stroke and transient ischemic attack (TIA). Postoperative TIA occurred in 3/1,357(0.2%); only one had moderate stenosis. Inhospital stroke occurred in 21/1,357 (1.5%) patients; stroke rates were 2.3% (8/355) with moderate stenosis and 2.1% (1/48) severe stenosis. There were 59/1,357 (4.3%) deaths; patients with stenosis had a mortality rate of 4.2% (17/403); however, no postoperative stroke lead to death. Multivariable logistic regression analysis with adjustment for age, gender, race, comorbidities, and postoperative complications did not show an impact of carotid stenosis on postoperative mortality and development of stroke after cardiac surgery.
Conclusion:
This study suggests that patients with asymptomatic carotid stenosis undergoing cardiac surgery are not at increased risk of postoperative complications and mortality; thus, prophylactic carotid revascularization may not be indicated.
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