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Association Between Brain Care Score and Cognitive Performance: Findings From a Community-Based Cohort in Singapore
Li Feng Tan1, Jasper R Senff2,3, Shuna Shiann Khoo4
1Healthy Ageing Program, Alexandra Hospital, Singapore, Singapore.
Brain and Behavior
|May 8, 2026
Summary
The Brain Care Score (BCS) is linked to better cognitive function. Higher BCS scores indicate healthier brain profiles and reduced odds of cognitive impairment in community populations.
Area of Science:
- Neuroscience
- Public Health
- Gerontology
Background:
- The Brain Care Score (BCS) is a novel instrument designed to quantify modifiable risk factors pertinent to brain health.
- Assessing brain health is crucial for developing effective public health strategies and interventions.
Purpose of the Study:
- To investigate the association between the Brain Care Score (BCS) and cognitive performance within a community-based cohort in Singapore.
- To determine if BCS can serve as a useful tool for assessing brain health risks in diverse populations.
Main Methods:
- Utilized data from the Health District @ Queenstown baseline study, a multiethnic community cohort.
- Calculated BCS (0-21 scale) from baseline questionnaires covering physical, lifestyle, and socioemotional factors.
- Assessed cognitive recall using the five-item word recall test and executive function via the Eriksen flanker task.
Main Results:
- A total of 5224 participants (mean age 52.8 years) were included in the analysis.
- Participants with cognitive impairment exhibited significantly lower mean BCS compared to those without impairment (14.9 vs. 16.2, p < 0.001).
- Each one-point increase in BCS was associated with a 5% reduction in the odds of impaired recall (OR 0.95) and a 0.03-point increase in executive function score (β 0.03).
Conclusions:
- Higher Brain Care Score (BCS) is significantly associated with better cognitive performance, including recall and executive function.
- The BCS demonstrates potential as a valuable community-based tool for assessing brain health and associated risks, particularly in Asian populations.
- Findings support the utility of BCS in identifying individuals who may benefit from interventions aimed at improving brain health.
