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Related Experiment Video

Updated: Mar 25, 2026

Exploring Infant Sensitivity to Visual Language using Eye Tracking and the Preferential Looking Paradigm
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[PREFERE - Study on the rise].

Carsten-H Ohlmann1, Michael Stöckle2, Peter Albers3

  • 1Klinik für Urologie und Kinderurologie, Universitätsklinikum des Saarlandes, Kirrbergerstr., 66421, Homburg/Saar, Deutschland. carsten.ohlmann@uks.eu.

Der Urologe. Ausg. A
|February 25, 2016
PubMed
Summary
This summary is machine-generated.

The PREFERE study for low-risk prostate cancer saw increased patient recruitment after revising its criteria. This allows broader patient inclusion, including those previously ineligible for certain treatments, enhancing study progress.

Keywords:
BrachtherapyImage-guided biopsyPatient selectionProstatectomyProstatic neoplasmsRadiotherapy

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Area of Science:

  • Oncology
  • Urology
  • Clinical Trials

Background:

  • The PREFERE study investigates treatment options for low and early intermediate-risk prostate cancer.
  • Patient recruitment trends prior to mid-2015 indicated a need for revised study parameters.

Purpose of the Study:

  • To analyze the impact of revised inclusion criteria on patient recruitment for the PREFERE study.
  • To facilitate broader patient enrollment in prostate cancer treatment comparisons.

Main Methods:

  • The study revised inclusion criteria to incorporate advanced imaging techniques like MRI and C-Trus.
  • Expanded eligibility to include all Gleason 3+3=9 cancers and patients with contraindications to radiotherapy or brachytherapy.
  • Enabled randomization between active surveillance and radical prostatectomy for specific patient groups.

Main Results:

  • A significant increase in patient recruitment was observed starting mid-2015.
  • Revised criteria successfully broadened the scope of eligible participants.
  • The study is now on track to meet its recruitment milestones.

Conclusions:

  • Revised inclusion criteria have demonstrably improved patient recruitment for the PREFERE study.
  • The study modifications enhance the potential for robust comparative analysis of prostate cancer treatments.
  • Widespread support within Germany has contributed to the study's recruitment success.