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Updated: Mar 25, 2026

08:46
Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
Published on: September 16, 2021
6.8K
Revised guidelines for good practice in IVF laboratories (2015)
, Maria José De los Santos1, Susanna Apter2
1IVI Valencia, Valencia, Spain mariajose.delossantos@ivi.es.
Human Reproduction (Oxford, England)
|February 25, 2016
Summary
This guideline offers recommendations for organizing and managing in vitro fertilization (IVF) laboratories. It aims to improve laboratory practices and enhance IVF patient care by providing expert advice.
Area of Science:
- Reproductive Medicine
- Embryology
- Laboratory Management
Background:
- Existing guidelines for IVF laboratory practices require updates.
- Expert consensus is needed to standardize IVF laboratory organization and management.
Purpose of the Study:
- To provide updated recommendations for the European Society of Human Reproduction and Embryology Special Interest Group (ESHRE SIG) Embryology.
- To support laboratory specialists in optimizing IVF laboratory organization, management, and patient care.
Main Methods:
- A guideline development group of 10 embryologists evaluated and rewrote existing guidelines.
- Recommendations were discussed and refined through consensus during two 2-day meetings.
- The draft guideline was reviewed by members of the ESHRE SIG embryology.
Main Results:
- Recommendations cover general IVF laboratory organization: staffing, quality management, and safety.
- Specific procedural recommendations include patient identification, oocyte retrieval, sperm preparation, insemination, embryo culture, and cryopreservation.
- Guidance is also provided on emergency planning for IVF laboratories.
Conclusions:
- The guideline provides comprehensive recommendations for good practice in IVF laboratory organization and procedures.
- Despite limited direct evidence, the recommendations are based on existing documents and expert consensus.
- This guideline is expected to be a valuable resource for IVF laboratory directors, managers, and technicians.

