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Is 131I ablation necessary for patients with low-risk papillary thyroid carcinoma and slightly elevated stimulated
Pedro Weslley Rosario1, Gabriela Franco Mourão1
1Santa Casa de Belo Horizonte, Belo Horizonte, MG, Brazil.
Objective:
This prospective study evaluated the recurrence rate in low-risk patients with papillary thyroid cancer (PTC) who presented slightly elevated thyroglobulin (Tg) after thyroidectomy and who did not undergo ablation with131I.
Subjects And Methods:
The study included 53 low-risk patients (nonaggressive histology; pT1b-3, cN0pNx, M0) with slightly elevated Tg after thyroidectomy (> 1 ng/mL, but ≤ 5 ng/mL after levothyroxine withdrawal or ≤ 2 ng/mL after recombinant human TSH).
Results:
The time of follow-up ranged from 36 to 96 months. Lymph node metastases were detected in only one patient (1.9%). Fifty-two patients continued to present negative neck ultrasound. None of these patients without apparent disease presented an increase in Tg.
Conclusions:
Low-risk patients with PTC who present slightly elevated Tg after thyroidectomy do not require ablation with 131I.
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