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Related Concept Videos

DNA Microarrays02:34

DNA Microarrays

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Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...
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Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases
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NABIC Microarray: an integrated database of high throughput data for gene expression profiles.

Jae-Hee Lee1, Sang-Ho Kang1, Jong-Yeol Lee2

  • 1Genomics Division, National Academy of Agricultural Science (NAAS), RDA, Jeonju 560-500, Republic of Korea.

Bioinformation
|February 26, 2016
PubMed
Summary
This summary is machine-generated.

The National Agricultural Biotechnology Information Center (NABIC) developed a free online database for gene expression profiles in microorganisms, plants, and animals. This resource offers search, viewing, and download functionalities for microarray data.

Keywords:
DNA microarrayNABIC microarraygene expression profile

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Area of Science:

  • Agricultural Biotechnology
  • Bioinformatics
  • Genomics

Background:

  • Gene expression profiling is crucial for understanding biological processes across various organisms.
  • Access to curated gene expression data facilitates research and discovery in agriculture and biotechnology.
  • The National Agricultural Biotechnology Information Center (NABIC) in Korea addresses the need for centralized biological data.

Purpose of the Study:

  • To establish a comprehensive, web-based database for gene expression profiles.
  • To provide researchers with tools for searching, viewing, and downloading microarray data.
  • To consolidate information on microorganisms, plants, and animals within a single platform.

Main Methods:

  • Construction of a web-based database system.
  • Archiving of NABIC microarray data, including metadata, matrix spreadsheets, and raw data files.
  • Implementation of search, viewer, and download functionalities for user accessibility.

Main Results:

  • A functional online database (http://nabic.rda.go.kr/DNAchip) is now available.
  • The database contains detailed information organized into five fields: ownership, basic, series, samples, and protocols.
  • Users can efficiently search, view, and download DNA microarray data for diverse organisms.

Conclusions:

  • The NABIC database serves as a valuable resource for agricultural biotechnology research.
  • Enhanced data accessibility promotes further investigation into gene expression patterns.
  • The platform supports scientific advancement by providing integrated gene expression information.