Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Advancing mechanobiology from single molecules to complex cellular systems.

Nature nanotechnology·2026
Same author

Correction to "How Effective Are Polyethylene Terephthalate/Polyurethane Nanofibers in Promoting Vascular Tissue Engineering? Structural, Mechanical, In Vitro and In Vivo Performance".

ACS applied bio materials·2026
Same author

Effective degradation of Reactive Blue 21 and Reactive Red 195 by copper(II) oxide nanoparticles biosynthesized by pistachio hulls extract.

Scientific reports·2026
Same author

Nanoengineered 3D culture substrate enables superior persistence and polyclonal engraftment of genetically engineered hematopoietic stem cells.

Cell stem cell·2026
Same author

How Effective Are Polyethylene Terephthalate/Polyurethane Nanofibers in Promoting Vascular Tissue Engineering? Structural, Mechanical, In Vitro, and In Vivo Performance.

ACS applied bio materials·2025
Same author

Development of a novel small diameter vascular graft based on an electrospun blend PET/PU scaffold: from fabrication to structural, mechanical, and in vitro evaluation.

Journal of materials science. Materials in medicine·2025

Related Experiment Video

Updated: Mar 25, 2026

Hollow Fiber Bioreactors for In Vivo-like Mammalian Tissue Culture
08:28

Hollow Fiber Bioreactors for In Vivo-like Mammalian Tissue Culture

Published on: May 26, 2016

17.1K

Hollow fiber bioreactor technology for tissue engineering applications.

Hadis Eghbali1,2, Michele M Nava3, Davod Mohebbi-Kalhori1

  • 1Department of Chemical Engineering, University of Sistan and Baluchestan, Zahedan - Iran.

The International Journal of Artificial Organs
|February 27, 2016
PubMed
Summary

Hollow fiber bioreactors offer excellent mass transport for in vitro tissue and organ engineering. This review classifies bioreactor types and discusses their applications and future potential in regenerative medicine.

More Related Videos

Designing a Bioreactor to Improve Data Acquisition and Model Throughput of Engineered Cardiac Tissues
12:28

Designing a Bioreactor to Improve Data Acquisition and Model Throughput of Engineered Cardiac Tissues

Published on: June 2, 2023

3.3K
Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids
08:22

Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids

Published on: August 11, 2017

16.5K

Related Experiment Videos

Last Updated: Mar 25, 2026

Hollow Fiber Bioreactors for In Vivo-like Mammalian Tissue Culture
08:28

Hollow Fiber Bioreactors for In Vivo-like Mammalian Tissue Culture

Published on: May 26, 2016

17.1K
Designing a Bioreactor to Improve Data Acquisition and Model Throughput of Engineered Cardiac Tissues
12:28

Designing a Bioreactor to Improve Data Acquisition and Model Throughput of Engineered Cardiac Tissues

Published on: June 2, 2023

3.3K
Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids
08:22

Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids

Published on: August 11, 2017

16.5K

Area of Science:

  • Biomedical Engineering
  • Regenerative Medicine
  • Tissue Engineering

Background:

  • Hollow fiber bioreactors (HFBs) are crucial for mimicking physiological vascular networks.
  • Their excellent mass transport properties overcome nutrient diffusion limitations in vitro.
  • This facilitates the engineering of sizable tissue and organ constructs.

Purpose of the Study:

  • To review the literature on hollow fiber bioreactors in organ and tissue engineering.
  • To classify HFBs into cylindrical and rectangular categories.
  • To summarize their applications and discuss future perspectives.

Main Methods:

  • Literature review of existing research on HFBs.
  • Classification of HFBs into cylindrical and rectangular types.
  • Summary of applications at tissue and organ levels, including experimental and computational studies.

Main Results:

  • HFBs are categorized into cylindrical and rectangular designs.
  • Applications span tissue-level constructs to whole organ engineering.
  • Experimental models and computational studies are key for designing dynamic culture systems.

Conclusions:

  • Hollow fiber bioreactors are versatile tools for in vitro organ and tissue engineering.
  • Continued research and development promise innovative dynamic culture systems.
  • HFBs hold significant future potential for regenerative medicine applications.