Enrofloxacin: a new antimicrobial agent

A review is given of available literature on a new antimicrobial agent, enrofloxacin. The chemical is a quinolone carboxylic acid derivative, and has a broad spectrum of activity against Gram-positive and Gram-negative bacteria as well as against Mycoplasma spp. in various animals. Several formulations and routes of administration have been tested, and equally good absorption and efficacy have been demonstrated after oral and parenteral administration. In South Africa, a 10% solution for use in the drinking water of poultry, has been registered, while different formulations for other species are still under development.