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Related Experiment Videos

Enrofloxacin: a new antimicrobial agent.

J Schroder1

  • 1Bayer (SA) Animal Health Division, Isando, Republic of South Africa.

Journal of the South African Veterinary Association
|June 1, 1989
PubMed
Summary

Enrofloxacin, a quinolone carboxylic acid derivative, shows broad-spectrum antimicrobial activity against various bacteria and Mycoplasma in animals. It is effective via oral and parenteral routes, with a poultry formulation registered in South Africa.

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Area of Science:

  • Veterinary Pharmacology
  • Antimicrobial Agents

Background:

  • Enrofloxacin is a novel quinolone carboxylic acid derivative.
  • It exhibits broad-spectrum antimicrobial activity.

Purpose of the Study:

  • To review available literature on enrofloxacin.
  • To assess its efficacy and formulations in various animal species.

Main Methods:

  • Literature review of enrofloxacin studies.
  • Analysis of different formulations and administration routes.
  • Evaluation of absorption and efficacy data.

Main Results:

  • Enrofloxacin is effective against Gram-positive and Gram-negative bacteria and Mycoplasma spp.
  • Oral and parenteral administration show comparable absorption and efficacy.
  • A 10% enrofloxacin solution for poultry drinking water is registered in South Africa.

Conclusions:

  • Enrofloxacin is a promising antimicrobial agent for veterinary use.
  • Further development of formulations for other animal species is ongoing.
  • The drug demonstrates significant potential in treating bacterial and mycoplasmal infections in animals.

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