Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Lifestyle Factors and Health01:20

Lifestyle Factors and Health

589
Lifestyle factors play a critical role in maintaining overall health and preventing chronic diseases. Key elements, such as regular physical activity, a nutritious diet, and abstinence from smoking, can significantly enhance physical, mental, and emotional well-being while reducing the risk of several life-threatening conditions.
Benefits of Physical Activity
Physical activity, whether through structured exercise or casual activities like walking, biking, or dancing, is a cornerstone of a...
589
Exercise and Cardiac Output01:17

Exercise and Cardiac Output

2.5K
Regular physical activity is essential for maintaining cardiovascular health, with aerobic exercises being particularly effective. According to the American Heart Association, 150 minutes of moderate to intense aerobic exercise per week is recommended for a healthy heart. Aerobic activities may include brisk walking, running, bicycling, cross-country skiing, and swimming, ideally performed three to five times per week.
Sustained exercise increases the muscles' oxygen demand, which can be...
2.5K
Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

5.0K
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
5.0K
Actuarial Approach01:20

Actuarial Approach

359
The actuarial approach, a statistical method originally developed for life insurance risk assessment, is widely used to calculate survival rates in clinical and population studies. This method accounts for participants lost to follow-up or those who die from causes unrelated to the study, ensuring a more accurate representation of survival probabilities.
Consider the example of a high-risk surgical procedure with significant early-stage mortality. A two-year clinical study is conducted,...
359
Assumptions of Survival Analysis01:15

Assumptions of Survival Analysis

484
Survival models analyze the time until one or more events occur, such as death in biological organisms or failure in mechanical systems. These models are widely used across fields like medicine, biology, engineering, and public health to study time-to-event phenomena. To ensure accurate results, survival analysis relies on key assumptions and careful study design.
484
Atherosclerosis III: Management01:26

Atherosclerosis III: Management

576
Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
576

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Estimation of the burden of Lyme borreliosis in Austria using hospital discharge data.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases·2026
Same author

First-in-human study of lomvastomig, a PD-1-TIM-3 bispecific antibody, in patients with advanced and/or metastatic solid tumors.

Journal for immunotherapy of cancer·2026
Same author

Advanced Paternal Age Reduces Live Birth Rates in Normospermic Men Undergoing ART: A Large Retrospective Cohort Study.

Andrology·2026
Same author

Optimising the Diagnosis of Sesame Seed Allergy With the Basophil Activation Test.

Allergy·2026
Same author

Systematic literature review of economic studies on nature-based social prescribing for health improvement.

BMC primary care·2026
Same author

Basophil Activation Test as Biomarker of Severity and Threshold of Allergic Reactions to Cow's Milk During Oral Food Challenges.

Allergy·2025

Related Experiment Video

Updated: Mar 25, 2026

Visualization of Intensity Levels to Reduce the Gap Between Self-Reported and Directly Measured Physical Activity
05:59

Visualization of Intensity Levels to Reduce the Gap Between Self-Reported and Directly Measured Physical Activity

Published on: March 7, 2019

7.3K

Replacing Sedentary Time with Physical Activity in Relation to Mortality.

Daniela Schmid1, Cristian Ricci, Sebastian E Baumeister

  • 11Department of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, GERMANY; and 2Institute for Community Medicine, University Medicine Greifswald, GERMANY.

Medicine and Science in Sports and Exercise
|February 27, 2016
PubMed
Summary

Replacing sedentary time with physical activity significantly reduces mortality risk. Even light activity offers benefits, while moderate to vigorous activity provides substantial protection against premature death.

More Related Videos

Physical Activity Measurement in Children Accepting Table Tennis Training
06:51

Physical Activity Measurement in Children Accepting Table Tennis Training

Published on: July 27, 2022

2.6K
Short Session High Intensity Interval Training and Treadmill Assessment in Aged Mice
09:19

Short Session High Intensity Interval Training and Treadmill Assessment in Aged Mice

Published on: February 2, 2019

10.6K

Related Experiment Videos

Last Updated: Mar 25, 2026

Visualization of Intensity Levels to Reduce the Gap Between Self-Reported and Directly Measured Physical Activity
05:59

Visualization of Intensity Levels to Reduce the Gap Between Self-Reported and Directly Measured Physical Activity

Published on: March 7, 2019

7.3K
Physical Activity Measurement in Children Accepting Table Tennis Training
06:51

Physical Activity Measurement in Children Accepting Table Tennis Training

Published on: July 27, 2022

2.6K
Short Session High Intensity Interval Training and Treadmill Assessment in Aged Mice
09:19

Short Session High Intensity Interval Training and Treadmill Assessment in Aged Mice

Published on: February 2, 2019

10.6K

Area of Science:

  • Public Health
  • Epidemiology
  • Preventive Medicine

Background:

  • Limited data exists on the mortality benefits of replacing sedentary time with physical activity.
  • Understanding the impact of activity reallocation on mortality risk is crucial for public health interventions.

Purpose of the Study:

  • To investigate the association between replacing sedentary time with physical activity of varying intensities and mortality risk.
  • To quantify the mortality benefits of substituting sedentary behavior with light or moderate-to-vigorous physical activity.

Main Methods:

  • Utilized data from the National Health and Nutrition Examination Survey (2003-2006) with mortality follow-up through 2011.
  • Employed isotemporal substitution models with accelerometer-assessed sedentary time and physical activity in adults aged 50-85.
  • Controlled for potential confounders in multivariable analyses.

Main Results:

  • Replacing 30 minutes of sedentary time with light activity reduced mortality risk by 14%.
  • Substituting sedentary time with moderate-to-vigorous activity led to a 50% reduction in mortality risk.
  • Replacing light physical activity with moderate-to-vigorous activity decreased mortality risk by 42%.

Conclusions:

  • Reallocating sedentary time to physical activity, even light intensity, may offer protection against premature mortality.
  • Substituting light physical activity with moderate-to-vigorous activity is associated with significant protection from mortality.