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Smart lanthanide coordination polymer fluorescence probe for mercury(II) determination
Baoxia Liu1, Yankai Huang2, Xu Zhu1
1Henan Key Laboratory Cultivation Base of Nanobiological Analytical Chemistry, College of Chemistry and Chemical Engineering, Shangqiu Normal University, Shangqiu 476000, China.
Analytica Chimica Acta
|February 28, 2016
Summary
A novel lanthanide coordination polymer (LCP) probe, Tb-CIP/AMP, was developed for sensitive mercury ion (Hg2+) detection. This LCP nanosensor offers high selectivity and can detect Hg2+ in real-world samples like drinking water and urine.
Area of Science:
- Materials Science
- Analytical Chemistry
- Nanotechnology
Background:
- Lanthanide coordination polymers (LCPs) are emerging as versatile biosensor materials due to their tunable properties and luminescence.
- Developing selective and sensitive probes for heavy metal ion detection remains a critical challenge in environmental and biomedical monitoring.
Purpose of the Study:
- To design and synthesize a smart LCP-based probe for the sensitive and selective detection of mercury ions (Hg2+).
- To investigate the luminescence properties and sensing mechanism of the designed LCP probe.
Main Methods:
- A lanthanide coordination polymer probe, Tb-CIP/AMP (using terbium ions, ciprofloxacin, and adenosine monophosphate), was synthesized.
- The probe's luminescence response to Hg2+ was studied, focusing on fluorescence quenching mechanisms.
- The probe's selectivity, sensitivity, and applicability in real samples were evaluated.
Main Results:
- The Tb-CIP/AMP probe exhibited strong green luminescence, enhanced by adenosine monophosphate.
- Mercury ions (Hg2+) caused significant fluorescence quenching due to specific coordination interactions with adenosine monophosphate.
- The probe demonstrated excellent selectivity for Hg2+ with a low detection limit of 0.16 nM and was successfully applied to detect Hg2+ in drinking water and human urine samples.
Conclusions:
- The developed Tb-CIP/AMP LCP probe is a highly sensitive and selective nanosensor for Hg2+ detection.
- This strategy offers a promising platform for developing time-gated luminescence assays for biological and biomedical applications.
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